Setting out a vision for the civil service in Ireland
Barrington Anne +2 more
doaj +1 more source
Important Marine Mammal Areas celebrated—yet some are now in danger
Erich Hoyt +7 more
doaj +1 more source
DRLO-VANET: a deep reinforcement learning-based offloading framework for low-latency and energy-efficient task execution in VANETs. [PDF]
Neelima S, Sree SR, Ramakrishnaiah N.
europepmc +1 more source
Linacre Institute Symposium - The Clerical Sexual Abuse Crisis: Inpatient Treatment and Outpatient Psychiatric Evaluation Programs for Priests and Religious, Report of the Task Force of the Catholic Medical Association [PDF]
Task Force of the Catholic Medical Association
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Dynamic regulation of TASK-1 channels under cellular stress. [PDF]
Yu Y, Curry J, Tankersley S, Hu K.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Joint Cognitive Models Reveal Sources of Robust Individual Differences in Conflict Processing. [PDF]
Molloy MF +7 more
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Random Soldier Kinematogram: a novel tool for task-switching research in military context. [PDF]
Mecheri S +3 more
europepmc +1 more source

