Results 61 to 70 of about 7,344,765 (259)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Aprender inglés en el museo: Propuesta de tarea trasversal para el aula de inglés de ESO

open access: yesOdisea, 2017
Resumen: Esta tarea interdisciplinar muestra el potencial del patrimonio artístico, de museos y centros de interpretación como aulas abiertas para enseñanza/aprendizaje de lenguas y como elemento motivador para alumnado y profesorado.
Gemma Delicado Puerto
doaj   +1 more source

Le ludique dans les manuels de français du cycle primaire : enjeux et perspectives

open access: yesMultilinguales, 2020
In this article, we try to analyze a corpus which is composed of the playful activities suggested in the three French textbooks in order to show the importance of these tools in the developement ok skills of algerian learners. On the one hand, we seek to
Sofiane Harrache
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The systems psychodynamic leadership coaching experiences of nursing managers

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2010
The mostly linear and mechanistic nature of the nursing manager role is rapidly becoming more dynamic and systemic. The change involves task and people management within a constantly changing organisational identity, taking up multiple leadership roles ...
Frans Cilliers, Landa Terblanche
doaj   +1 more source

Face-to-face and online interactions - is a task a task? [PDF]

open access: yes, 2006
This study contrasts two different ways of analysing interaction and participation in language learning tutorials: Social network analysis of frequency and QSR analysis of type of interaction. One task from three German beginners' language tutorials (one
Batstone, Carolyn   +3 more
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Task Selection for Bandit-Based Task Assignment in Heterogeneous Crowdsourcing [PDF]

open access: yes, 2015
Task selection (picking an appropriate labeling task) and worker selection (assigning the labeling task to a suitable worker) are two major challenges in task assignment for crowdsourcing. Recently, worker selection has been successfully addressed by the
Sugiyama, Masashi, Zhang, Hao
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Critical Implications of IVDR for Innovation in Diagnostics: Input From the BioMed Alliance Diagnostics Task Force

open access: yesHemaSphere, 2022
Isabel Dombrink   +10 more
doaj   +1 more source

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