Results 141 to 150 of about 784,511 (290)

Scenario-Based Serious Game for Screening Mild Cognitive Impairment in Older Adults: Cross-Sectional Preliminary Validation Study. [PDF]

JMIR Serious Games
Jeon B, Noh CH, Noh SR, Shim Y, Cho SB, Cho S.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis. [PDF]

Front Nutr
Wang R, Wang W, Meng L, Hao G, Gu G.
europepmc   +1 more source

Ego depletion and persistent performance in a cycling task

, 2015
We tested the assumption that persistent performance in an exhausting indoor cycling task would depend on momentarily available self-control strength (N = 20 active participants). In a within-subjects design (two points of measurement, exactly seven days
Wolff, Wanja, Englert, Christoph
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Assistive algorithms influence neural representations in motor brain-computer interfaces. [PDF]

Nat Commun
Rajeswaran P, Payeur A, Lajoie G, Orsborn AL.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Corrigendum: Effects of weight divisions in time-motion of female high-level Brazilian Jiu-jitsu combat behaviors

Frontiers in Psychology, 2023
Marco Antonio Ferreira dos Santos, Dany Alexis Sobarzo Soto, Michele Andrade de Brito, Michele Andrade de Brito, Ciro José Brito, Esteban Aedo-Muñoz, Esteban Aedo-Muñoz, Maamer Slimani, Nicola L. Bragazzi, Hela Znazen, Bianca Miarka   +10 more
doaj   +1 more source

chewR: An Open-Source R Package for Quantifying Masticatory Performance With Applications in Oral Processing Research. [PDF]

J Texture Stud
Long JW, Akanzinge E, Hayes JE.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source