Results 61 to 70 of about 2,689,429 (376)

Business process optimization based on information technology in communications of IT projects

open access: yesТехнічна інженерія, 2021
The relevance of the research topic is due to global trends in the development of IT technologies and the reorientation of domestic IT companies to a new type of management, based on modern information technologies and project management tools ...
O.M. , І.І. , І.В.
doaj   +1 more source

Open Source and Proprietary Project Management Tools for SMEs

open access: yes, 2016
The dimensional growth and increasing difficulty in project management promoted the development of different tools that serve to facilitate project management and track project schedule, resources and overall progress.
Veronika Abramova   +2 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Management and Information Support Issues in the Implementation of Innovation Projects in Production Systems

open access: yesProceedings of the International Conference on Applied Innovations in IT, 2019
The article investigates tasks and approaches related to the management of innovation projects, the current state of production and project management in production environment.
Leonid Mylnikov
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Systems Thinking in Software Projects-an Artificial Neural Network Approach

open access: yesIEEE Access, 2020
The authors discuss why the current conceptual base of project management research and practice continues to attract criticism since it does not adequately address the complexity that leads to software-project failure.
Zorica M. Mitrovic   +5 more
doaj   +1 more source

E-learning Aspects of NODES Project [PDF]

open access: yes, 2006
The NODES project aims at promoting the use, in adult training/lifelong learning, of multimedia knowledge, in order to facilitate competitiveness, employability and mobility of adults who are victims of the digital divide or of some of its components ...
Herdon, Miklós, Várallyai, László
core  

How entrepreneurial orientation can leverage innovation project portfolio management

open access: yesR&D Management, 2020
Innovation project portfolio management (IPPM) is a key task in R&D management because this decision-making process determines which R&D projects should be undertaken and how R&D resources are allocated.
Alexander Kock, H. Gemünden
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Problems of project management software implementation in construction corporations

open access: yesMATEC Web of Conferences, 2016
The article is devoted to the main problems facing many companies, implementing software project management activities have been working construction corporation.
Kagan Pavel, Naumova Anna, Vilman Yuriy
doaj   +1 more source

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