Results 101 to 110 of about 53,306 (313)
Hybrid Max-Min Genetic Algorithm for Load Balancing and Task Scheduling in Cloud Environment
, 2020 Shilpa Kodli, Sujatha Terdal
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Multi-AGV Scheduling and Path Planning Based on an Improved Ant Colony Algorithm
VehiclesIn current intelligent manufacturing workshops, multi-automated guided vehicle (AGV) systems often face issues such as uneven task allocation, path conflicts, and idle travel, which significantly affect scheduling efficiency.
Yang Xu, Wei Liu, Hao Yuan
doaj +1 more source
Minimal Task Allocation in Multiprocessors using improved next-fit for RM scheduling
, 2012 Muthu KumarB, Anju S. Pillai
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Hybrid Algorithm Based on Swarm Intelligence Techniques for Dynamic Tasks Scheduling in Cloud Computing [PDF]
, 2016 Medhat A. Tawfeek, Gamal Farouk Elhady
openalex +1 more source
Online Task Scheduling for Fog Computing with Multi-Resource Fairness [PDF]
, 2020 Simeng Bian, Xi Huang, Ziyu Shao
openalex +1 more source