Results 121 to 130 of about 3,354,478 (288)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Industry and Public Sector Cooperation for Information Sharing: Ports of Long Beach & Los Angeles / September 2008 [PDF]
, 2008 (MIST Long Beach/LA)On August 20-21, the Maritime Information Sharing Taskforce (MIST) held a workshop at the Los Angeles/Long Beach Port (LA/LB). This workshop was funded by the Assistant Secretary of Defense, (Department of Homeland Defense) and ...
Walsh, Wendy +2 more
core
, 2022 Origins of the Monitoring, Evaluation and Learning, Communities of Practice (CoP) & Task Force on ...
CGIAR Indicator Task Force
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Frontiers in NeurologySub-Saharan Africa (SSA) bears a disproportionate burden of neurological and pain-related diseases while facing a severe shortage of trained specialists.
Daniele Martinelli +4 more
doaj +1 more source
MTEQA at WMT21 Metrics Shared Task.
, 2021 In this paper, we describe our submission to the WMT 2021 Metrics Shared Task. We use the automatically-generated questions and answers to evaluate the quality of Machine Translation (MT) systems. Our submission builds upon the recently proposed MTEQA framework.
Mateusz Krubinski +3 more
openaire +2 more sources
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
South Carolina Human Trafficking Task Force newsletter
, 2019 This quarterly newsletter is released by the South Carolina Human Trafficking Task Force. As South Carolina's anti-human trafficking movement continues to grow, the State Task Force designed this newsletter to promote information sharing and ...
South Carolina Human Trafficking Task Force
core +2 more sources
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source