Results 61 to 70 of about 42,611 (302)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Taste-Active Maillard Reaction Products in Roasted Garlic (Allium sativum)

open access: yes, 2016
In order to gain first insight into candidate Maillard reaction products formed upon thermal processing of garlic, mixtures of glucose and S-allyl-l-cysteine, the major sulfur-containing amino acid in garlic, were low-moisture heated, and nine major ...
Junichiro Wakamatsu (1548178)   +2 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Food neophobia and its association with taste threshold and food liking among adults

open access: yes, 2023
This study was designed to determine the relationship between taste threshold (sweet, bitter, sour, salt, fat), food neophobia and food liking. A total of 51 non-smoking and healthy individuals were recruited in Ankara, Turkey.
DİKMEN, DERYA, Ozturk, Elif Esra
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Assessment and evaluation of gustatory functions in patients with diabetes mellitus Type II: A study

open access: yesIndian Journal of Endocrinology and Metabolism, 2018
Introduction: The assessment of taste is critically important for an individual to enjoy life. This however, gets altered in various diseases. Diabetes Mellitus is one of the diseases in which person has dysgeusia.
Shriya Khera, Anjali Saigal
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The difference of sweet taste threshold before and after using mouthwash containing zinc sulfate

open access: yesPadjadjaran Journal of Dentistry, 2010
Introduction: Mouthwash containing zinc sulfate could reduce the ability of tasting sweetness temporarily. Zinc sulfate is an example of a zinc compound which is the active ingredient in mouthwash.
Agung Ayu Dewi Janarikamain   +2 more
doaj   +1 more source

Evaluation of the Sensory Perception of Sweet Taste in People with Diabetes Mellitus Type 1 in Indian Population: A Comparative Study [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2021
Background: Taste perception is an integral part of a person’s life. This perception gets altered due to many factors, one of which is diabetes mellitus. There is limited data on the taste alteration for sweet in Type 1 diabetics.
Uma Maheshwari G., Manju Latha K.
doaj  

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