Results 31 to 40 of about 22,631 (118)

A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication [PDF]

, 2011
Background Gene trap insertional mutagenesis was used as a high-throughput approach to discover cellular genes participating in viral infection by screening libraries of cells selected for survival from lytic infection with a variety of ...
Brian M Friedrich, James L Murray, Guangyu Li, Jinsong Sheng, Thomas W Hodge, Donald H Rubin, William A O'Brien, Monique R Ferguson   +7 more
core   +1 more source

Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization. [PDF]

, 2018
Lentiviral vector mobilization following HIV-1 infection of vector-transduced cells poses biosafety risks to vector-treated patients and their communities.
Bi, Yanmin, Fry, Nate J, Hu, Peirong, Kafri, Tal, Kohn, Donald B, Ma, Hong, Suwanmanee, Thipparat, Zeithaml, Brian   +7 more
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Using death to one's advantage: HIV modulation of apoptosis [PDF]

, 2001
Infection by human immunodeficiency virus (HIV) is associated with an early immune dysfunction and progressive destruction of CD4+ T lymphocytes. This progressive disappearance of T cells leads to a lack of immune control of HIV replication and to the ...
A Algeciras, A Anel, A Badley, A Cafaro, A Greeway, A Kelekar, A Kinter, AD Osterhaus, AG Laurent-Crawford, AH Wyllie, AJ Darmon, AJ Minn, AL Van, AM Chinnaiyan, AS Baur, B Conradt, B Ensoli, BR Cullen, BR Gundlach, C Aiken, C Baumler, C Cicala, C Cicala, C Terai, CA Ray, CD Bortner, D Ho, D Reinhold, D Xue, D Zagury, D Zagury, DE Croal, DF Nixon, DiMarzio, DJ Li, DK Miller, DN Levy, DR Hodge, E Rapaport, EA Cohen, EB Stephens, EN Kraiselburd, ES Alnemri, ET Sawai, ET Sawai, F Cocchi, F Margottin, F Re, G Alkhatib, G Alkhatib, G Hacker, G Herbein, G Herbein, G Pan, G Zauli, GD Edwart, GL Stivahtis, H Choe, H Deng, H Okada, HL Robinson, I Agostini, I Szabo, J Bertin, J Dhein, J Estaquirer, J He, J Hesselgesser, J Hua, J Lama, J Savill, JBM Jowett, JC Ameisen, JC Ameisen, JC Reed, JE Rosok, JG Teodoro, JM Adams, JV Garcia, JW Balliet, K Ogawa, K Shasty, K Strebel, KA Jones, KL Collins, KM Murphy, KP Wilson, L Alexander, L Meyaard, L Selig, L Wang, L Zheng, LM Mansky, LT Quan, M Alderson, M Bouhamdan, M Ui, M Westendorp, MA Vodicka, MC Gauduin, MD Hazenberg, ME Rogel, MG Hengartner, MS Wyand, MX Wu, N Chirmule, N Hattori, NK Heinzinger, P Gallay, PA Sandstrom, PD Katsikis, PD Katsikis, PJ Maddon, R Antonasson, R Gehri, RA Black, RI Connor, RJ Clem, RP Viscidi, RT Allen, S Bour, S Hodge, S Mahalingam, S Schendel, S Sieg, S Wang, S-T Ju, SA Stewart, SF Purvis, SR Bartz, SR D'Mello, SS Cohen, T Brunner, TH Finkel, TM Ross, TM Ross, U Schubert, V Cryns, V Cryns, V Kolensnitchenko, W Paxton, WMS Guntheil, X Lu, X-J Yao, X-N Xu, Y Collette, Y Hu, YBC Feng, YL Lu, Z Wang   +149 more
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In vitro dynamics of HIV-1 BF intersubtype recombinants genomic regions involved in the regulation of gene expression [PDF]

, 2009
HIV-1 intersubtype recombination is a very common phenomenon that has been shown to frequently affect different viral genomic regions. Vpr and Tat are viral proteins known to interact with viral promoter (LTR) during the replication cycle.
Carobene, Mauricio, Rodríguez Rodrígues, Christian Fernando Ariel, de Candia, Cristian Ariel, Turk, Gabriela Julia Ana, Salomon, Horacio Eduardo   +4 more
core   +2 more sources

The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. [PDF]

, 2019
A major challenge in finding a cure for HIV-1/AIDS is the difficulty in identifying and eradicating persistent reservoirs of replication-competent provirus.
Chang, Kungyen, Chao, Ti-Chun, Karris, Maile Ann Young, Kaul, Marcus, Li, Zhonghan, Qin, Yue, Rana, Tariq M, Sanchez, Ana, Singh, Gatikrushna, Tiwari, Shashi Kant, Yau, Edwin, Zhang, Qiong   +11 more
core   +1 more source

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]

, 1988
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H., Hood, Leroy E., Jameson, Bradford A., Kappes, John C., Kent, Stephen B. H., Lee, Shei-Wen, Morrow, Casey D., Shaw, George M.   +7 more
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EFFICIENT PROPAGATION OF ARCHETYPE JC POLYOMAVIRUS IN COS-7 CELLS: EVALUATION OF REARRANGEMENTS WITHIN NCCR STRUCTURAL ORGANIZATION DURING TRANSFECTION. [PDF]

, 2017
John Cunningham virus (JCPyV) is an ubiqui-tous human pathogen that causes disease in immunocom-promised patients. The JCPyV genome is composed of an early region and a late region, which are physically sepa-rated by the ...
Anzivino, Elena, Bellizzi, Anna, Palamara, ANNA TERESA, Pietropaolo, Valeria Antonietta, Prezioso, Carla, Rodio, DONATELLA MARIA, Scribano, D, Trancassini, Maria   +7 more
core   +1 more source

Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr) [PDF]

, 2009
Peptides that are capable of traversing the cell membrane, via protein transduction domains (PTDs), are attractive either directly as drugs or indirectly as carriers for the delivery of therapeutic molecules. One such PTD, a HIV-1 Tat derived peptide has
Choo, A. Y., Chung, J. C. W., Kim, J. J., Lambert, V. M., Muthumani, K., Satishchandran, A., Shanmugam, M., Thieu, K. P., Ugen, K. E., Weiner, D. B.   +9 more
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The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery [PDF]

, 2004
© 2004 Anson; licensee BioMed Central Ltd. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction
Donald S Anson
core   +1 more source

A dual function TAR Decoy serves as an anti-HIV siRNA delivery vehicle [PDF]

, 2010
The TAR RNA of HIV was engineered as an siRNA delivery vehicle to develop a combinatorial therapeutic approach. The TAR backbone was found to be a versatile backbone for expressing siRNAs.
Hoshang J Unwalla, John J Rossi, I Bahner, A Banerjea, A Michienzi, S Escaich, I Plavec, HJ Unwalla, NJ Caplen, SM Elbashir, TR Brummelkamp, NS Lee, PY Chen, CA Kidner, SY Ying, LA Aagaard, S Barth, E Gottwein, F Grey, DL Ouellet, TM Rana, M Yang, MJ Churcher, DH Kim, BJ Calnan, D Castanotto, P Kumar, J Zhou, J Sambrook, HJ Unwalla   +29 more
core   +1 more source