Results 41 to 50 of about 92,910 (287)

Highly expressed proteins have an increased frequency of alanine in the second amino acid position

open access: yesBMC Genomics, 2006
Background Although the sequence requirements for translation initiation regions have been frequently analysed, usually the highly expressed genes are not treated as a separate dataset. Results To investigate this, we analysed the mRNA regions downstream
Remm Maido, Tats Age, Tenson Tanel
doaj   +1 more source

Evolution Reinforces Cooperation with the Emergence of Self-Recognition Mechanisms: an empirical study of the Moran process for the iterated Prisoner's dilemma

open access: yes, 2017
We present insights and empirical results from an extensive numerical study of the evolutionary dynamics of the iterated prisoner's dilemma. Fixation probabilities for Moran processes are obtained for all pairs of 164 different strategies including ...
Campbell, Owen   +3 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Preferred and avoided codon pairs in three domains of life

open access: yesBMC Genomics, 2008
Background Alternative synonymous codons are not used with equal frequencies. In addition, the contexts of codons – neighboring nucleotides and neighboring codons – can have certain patterns.
Tenson Tanel, Tats Age, Remm Maido
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Prospective observational study of point-of-care creatinine in trauma. [PDF]

open access: yes, 2016
Background:Patients with trauma are at risk for renal dysfunction from hypovolemia or urological injury. In austere environments, creatinine values are not available to guide resuscitation. A new portable device, the Stat Sensor Point-of-care (POC) Whole
Carden, Anthony J   +6 more
core   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Benthic invertebrates that form habitat on deep banks off southern California, with special reference to deep sea coral [PDF]

open access: yes, 2006
There is increasing interest in the potential impacts that fishing activities have on megafaunal benthic invertebrates occurring in continental shelf and slope ecosystems.
Amend, Mark   +4 more
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Diversity of amphibians in rice fields from northeastern Argentina [PDF]

open access: yes, 2008
Se registró y analizó la diversidad y riqueza de una comunidad de anfibios que habita campos de arroz en el nordeste de Ar.gentina. Las muestras fueron obtenidas en el período comprendido entre octubre 2001 y junio 2003.
Duré Pitteri, Marta Inés   +3 more
core  

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