Results 41 to 50 of about 4,955 (252)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Preferred and avoided codon pairs in three domains of life
BMC Genomics, 2008 Background Alternative synonymous codons are not used with equal frequencies. In addition, the contexts of codons – neighboring nucleotides and neighboring codons – can have certain patterns.
Tenson Tanel, Tats Age, Remm Maido
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
TATS CRU INC. THE MURAL KINGS INNOVATORS OF URBAN ADVERTISING [PDF]
, 2003 https://digitalcommons.ric.edu/rits/1098/thumbnail ...
Tats Cru Inc.
core
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Automatisation du processus de mise en place des ?tats financiers : application : KPMG Alg?rie [PDF]
, 2022 M?moire de Projet de Fin d??tudes : G?nie Industriel. Management industriel : Alger, ?cole Nationale Polytechnique : 2022.L?objectif de ce travail est d?automatiser moyennant le Robotic Process Automation (RPA) le processus m?tier de mise en place des ...
Benmeradi, Hynd Manel, Ould Taleb, Anya
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Tạp chí Khoa học Đại học Cần Thơ, 2017 Nghiên cứu xác định sự biến đổi về hoạt tính enzyme tiêu hóa của ống tiêu hóa ở cá lóc bột được tiến hành từ ngày 1 đến ngày thứ 35 sau khi cá nở với 2 chế độ cho ăn khác nhau.
Ngô Minh Dung +4 more
doaj +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source