Results 41 to 50 of about 925,069 (322)
Frontiers in Aging Neuroscience, 2009 In this short review, I will focus on how a unique tau gene may produce many tau isoforms through alternative splicing and how the phosphorylation of these isoforms by different kinases may affect their activity and behaviour. Indeed, each of the different tau isoforms may play a distinct role under both physiological and pathological conditions. Thus,
openaire +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
LRR Voices: Health & Safety for Unorganized, Immigrant Workers [PDF]
, 1993 Pam Tau Lee is Labor Coordinator at the Labor Occupational Health Program at the University of California, Berkeley, and serves on the boards of the National Toxic Campaign Fund, National People of Color Environmental Summit, and the Chinese Progressive ...
Tau Lee, Pam
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Hypoxanthine Derivatives in Experimental Infections
Canadian Journal of Infectious Diseases, 1992 In vivo treatment with parenterally administered hypoxanthine derivatives, notably ST 789, was able to protect cyclophosphamide-immunosuppressed mice against experimental infections with both bacterial and fungal pathogens.
Claudio De Simone +7 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Targeting tauopathy with engineered tau-degrading intrabodies [PDF]
, 2019 BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies.
Gallardo, Gilbert +7 more
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Transverse $\tau$ polarization in $B_c \to \tau \bar \nu_{\tau} \gamma $ decay [PDF]
, 2002 The possible transverse polarization of the $\tau$-lepton, which is $T$-odd and can be used to measure CP-violation, is estimated precisely in the radiative decay mode $B_c \to \tau \bar \nu_\tau \gamma$ with possible parameters for the multi Higgs ...
Chang, Chao-Hsi +3 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Constraints on the non-standard interaction in propagation from atmospheric neutrinos [PDF]
, 2015 The sensitivity of the atmospheric neutrino experiments to the non-standard flavor-dependent interaction in neutrino propagation is studied under the assumption that the only nonvanishing components of the non-standard matter effect are the electron and ...
Fukasawa, Shinya, Yasuda, Osamu
core +3 more sources