Results 111 to 120 of about 111,755 (296)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai   +7 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Automated μFTIR Imaging Demonstrates Taxon-Specific and Selective Uptake of Microplastic by Freshwater Invertebrates

open access: green, 2021
Chang‐Gui Pan   +6 more
openalex   +2 more sources

DNA metabarcoding reveals greater plant diversity than morphological seed analysis of bird feces

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Fruit‐eating birds drive seed dispersal in recovering tropical ecosystems, shaping forest regeneration. Molecular techniques, such as DNA metabarcoding, enable diet analysis from feces and can provide complementary frugivory data where dispersal is infrequent, as well as aid in seed identification in hyper‐diverse regions lacking ...
Carina I. Motta   +3 more
wiley   +1 more source

Assessing the viability of genebanked seeds from rare, wild plants native to the United States using the D.E.A.D. paradigm

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Genebanks must maintain viable seeds for decades. Seeds that germinate are clearly alive, but some seeds, often from wild populations, do not germinate because they are dormant, empty, aged, or damaged (D.E.A.D.). This work evaluates the effects of D.E.A.D.
Christina Walters   +33 more
wiley   +1 more source

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