Results 211 to 220 of about 183,225 (261)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Measuring beta‐diversity from taxonomic similarity

Journal of Vegetation Science, 2007
AbstractQuestion: The utility of beta (β‐) diversity measures that incorporate information about the degree of taxonomic (dis)similarity between species plots is becoming increasingly recognized. In this framework, the question for this study is: can we define an ecologically meaningful index of β‐diversity that, besides indicating simple species ...
Carlo Ricotta, Giovanni Bacaro
exaly   +5 more sources

An Information-Theoretical Measure of Taxonomic Diversity

Acta Biotheoretica, 2003
Traditional diversity indices are computed from the abundances of species present and are insensitive to taxonomic differences between species. However, a community in which most species belong to the same genus is intuitively less diverse than another community with a similar number of species distributed more evenly between genera.
RICOTTA, Carlo, AVENA, Giancarlo
openaire   +2 more sources

Dynamics of taxonomic diversity

Paleobiology, 1980
A general model of taxonomic diversity, incorporating diversity-dependent rates of origination and extinction, is constructed to examine the dynamic responses of diversity to perturbation. The model predicts that the trajectories of diversification increase and decrease are substantially different.
Timothy R. Carr, Jennifer A. Kitchell
openaire   +1 more source

Rarefaction and Taxonomic Diversity

Biometrics, 1982
Rarefaction is a technique that corrects for unbalanced sample sizes, which are often a major problem in comparisons of diversity. The rarefaction curve is the expected number of higher taxonomic groups, such as families or genera, represented in a random selection of lower taxonomic units, such as species or individuals. The shapes of these curves are
John J. Gart   +2 more
openaire   +1 more source

Generation and Maintenance of Gradients in Taxonomic Diversity

Science, 1969
Latitudinal gradients in diversity of organisms represent an equilibrium distribution for at least the last 270 × 10 6 years. Faunas endemic to tropical regions evolved significantly faster than extra-tropical faunas.
F G, Stehli, R G, Douglas, N D, Newell
openaire   +2 more sources

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