Results 121 to 130 of about 1,055,208 (296)
Advanced Science, EarlyView.We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi +22 more
wiley +1 more source
Numerical Taxonomy Numerical Taxonomy
Caldasia, 1973 For some strange reason the attitudes of taxonomists and systematists towards the phrase "numerical taxonomy" fall into two extreme positions. On the one hand are those who think numerical taxonomy provides the only means of reaching objective conclusions, that any other approach to taxonomy is sterile, subjective, and really not quite scientific.
openaire +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
TAXONOMY DEVELOPMENT IN INFORMATION SYSTEMS: DEVELOPING A TAXONOMY OF MOBILE APPLICATIONS [PDF]
The complexity of the information systems field often lends itself to classification schemes, or taxonomies, which provide ways to understand the similarities and differences among objects under study. Developing a taxonomy, however, is a complex process
Henri Isaac +3 more
core
Advanced Science, EarlyView.A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding +6 more
wiley +1 more source
Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
Advanced Science, EarlyView.ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
A New Taxonomy of Economic sectors With a View to Policy Implications [PDF]
This paper is an attempt to tease out a taxonomy of economic sectors based on a systems approach to innovation and economic growth that may be useful for policy analysis.
Eduardo Pol +2 more
core
Forecasting Root Rot Disease through Predictive Microbial Functional Profiling
Advanced Science, EarlyView.Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You +11 more
wiley +1 more source