Results 191 to 200 of about 1,563,398 (336)

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

open access: yesAdvanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao   +13 more
wiley   +1 more source

Deciphering the Language of Assessment in Pharmacology Summative Written Assessments. [PDF]

open access: yesPharmacol Res Perspect
Kelly-Laubscher R   +3 more
europepmc   +1 more source

Toward Sustainable Pesticide Application: Bridging Efficacy and Food Safety

open access: yesAdvanced Science, EarlyView.
A fully bio‐based lignin coacervate system is developed for pesticide delivery, enhancing leaf retention, UV resistance, adhesion, and wetting. The formulation enables pH/laccase‐triggered release for prolonged action, reduces ecological toxicity, and is fully washable, reconciling agricultural efficacy with food and environmental safety.
Xuan Li   +4 more
wiley   +1 more source

GlobDB: a comprehensive species-dereplicated microbial genome resource. [PDF]

open access: yesBioinform Adv
Speth DR   +7 more
europepmc   +1 more source

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

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