Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy
Advanced Science, EarlyView.An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang +12 more
wiley +1 more source
Canopy functional composition as an indicator of bird traits, taxonomy, and vulnerability in tropical Peruvian forests. [PDF]
Nat CommunOlah G, Evans MJ, Asner GP.
europepmc +1 more source
Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems
Advanced Electronic Materials, EarlyView.Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang +9 more
wiley +1 more source
Two regions, two lineages: Untangling two centuries of confusion between Machilus glaucescens and M. macranthus (Lauraceae) through integrative taxonomy. [PDF]
PLoS OneMalakar N, Gudasalamani R, Rengaian G.
europepmc +1 more source
A Dual‐Branch Flux‐Based Extended Memristor Model With Machine‐Learning‐Assisted Calibration
Advanced Electronic Materials, EarlyView.Multilayer oxide memristors integrated in crossbar arrays are described through a dual‐branch, flux‐controlled compact model. A three‐stage calibration workflow combining Latin hypercube sampling, Bayesian optimization, and gradient‐based refinement extracts device parameters from experimental data.
Davide Rossetti +6 more
wiley +1 more source
A Systems-Based Approach for Analyzing Interorganizational Coordination Within Port Risk Control Structures. [PDF]
Risk AnalMeléndez E, Goerlandt F.
europepmc +1 more source
Hemp Cultivation and Crop Diversification: Implications for Ecosystem Services in Kentucky
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT This study examines the ecosystem benefits of expanding hemp cultivation by assessing its impact on crop diversity. Using scenario‐based simulations and fixed‐effect panel regressions with county‐level data in Kentucky, we find that increased hemp acreage tends to enhance crop diversity, improving water quality and bird diversity.
Yunsun Park +4 more
wiley +1 more source
A hardware-grounded energy taxonomy for comparing deep and Spiking Neural Network inference on edge platforms. [PDF]
Front NeurosciEl-Hafci M, Sabri MA, Aarab A.
europepmc +1 more source
Extension Economists: Valued in Mission, Penalized in Practice
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT As the public engagement arm of the land‐grant mission, we argue that Extension faculty in US agricultural economics departments face an identity crossroads as they struggle for institutional support. Specifically, we argue that Extension economists function as boundary‐spanning professionals within academic structures that often devalue ...
Trey Malone +5 more
wiley +1 more source
Correction to: Flower development and morphoanatomy of Dendrophthora costaricensis Urb. (Viscaceae) and its implications in the taxonomy of Phoradendreae. [PDF]
ProtoplasmaYañez-Macias AV +2 more
europepmc +1 more source