Summary Paclitaxel is one of the most effective anticancer drugs ever developed. Although the most sustainable approach to its production is provided by plant cell cultures, the yield is limited by bottleneck enzymes in the taxane biosynthetic pathway: baccatin‐aminophenylpropanoyl‐13‐O‐transferase (BAPT) and 3′‐N‐debenzoyltaxol N‐benzoyltransferase ...
Edgar Perez‐Matas +4 more
wiley +1 more source
This study employs an ensemble modeling approach to systematically assess the impacts of human activities and climate change on suitable habitats of five Taxus species in China (T. wallichiana var. mairei, T. cuspidata, T. chinensis, T.
Jiahong Wang +7 more
doaj +1 more source
Structures of Taxchinins L and M, Two New Diterpenoids from Taxus chinensis var. Mairei.
The structures of two new diterpenoids, taxchinin L (1) and taxchinin M (2), from the leaves and stems of Taxus chinensis var. mairei were elucidated by means of NMR spectroscopy. These diterpenoids have an 11(15-->1)-abeo-taxane skeleton and exist as an equilibrium mixture of two conformers in CDCl3 at an ambient temperature.
TANAKA, Kiyoshi +5 more
openaire +2 more sources
Flavonoid Components, Distribution, and Biological Activities in Taxus: A review. [PDF]
Wei Q, Li QZ, Wang RL.
europepmc +1 more source
Research Advances in Clinical Applications, Anticancer Mechanism, Total Chemical Synthesis, Semi-Synthesis and Biosynthesis of Paclitaxel. [PDF]
Zhang S +7 more
europepmc +1 more source
An endophytic Taxol-producing fungus BT2 isolated from Taxus chinensis var. mairei
BT2, a newly isolated endophytic fungus from Taxus chinensis var. mairei, was observed to produce Taxol. Besides Taxol, a potent anticancer drug, BT2 could also yield taxane baccatin III, which was an important intermediate for Taxol and semi-synthesis of Taxol in industry.
Guo, BH +6 more
openaire +1 more source
Five Species of Taxus Karyotype Based on Oligo-FISH for 5S rDNA and (AG3T3)3. [PDF]
He Z, Luo X, Lei Y, Zhang W.
europepmc +1 more source
Chemical compositions and biological activities of the oils from the genus Taxus and factors limiting the regeneration of endangered yews: a review. [PDF]
Dhakal S, Khosla PK, Getahun T.
europepmc +1 more source
Transcription level differences in Taxus wallichiana var. mairei elicited by Ce3+, Ce4+ and methyl jasmonate. [PDF]
Han N +9 more
europepmc +1 more source

