Results 181 to 190 of about 69,416 (282)

Capital and the Family

open access: yesThe British Journal of Sociology, EarlyView.
ABSTRACT How are capital and the family interconnected in contemporary capitalism? In this article, we argue that they come together in owning relations. By owning capital across generations, families bridge the temporal gap between the durability of capital and the finite lifespan of private property holders and thus resolve the problem of bona ...
Jens Beckert, Isabell Stamm
wiley   +1 more source

Beyond abstinence: Redefining success in cannabis use disorder treatment

open access: yesAddiction, EarlyView.
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin   +3 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder   +7 more
wiley   +1 more source

Evaluating the Value of Tissue-Based Assays in the Diagnosis of AE. [PDF]

open access: yesRev Neurol
Fang Y   +11 more
europepmc   +1 more source

CDK4/6 Inhibitors and Curcumin Synergistically Suppress HER2− Breast Cancer via Lethal ROS and Inhibition of Metastasis

open access: yesCancer Science, EarlyView.
Schematic illustrating that CDK4/6 inhibitors combined with curcumin induce lethal ROS accumulation by disrupting redox balance, downregulating GPX4, and depleting glutathione, leading to DNA damage and lipid peroxidation. This oxidative stress triggers tumor cell death and suppresses EMT‐driven migration.
Chenyu Wang   +14 more
wiley   +1 more source

Countercation Manipulation Enables Selective Electrochemical CO<sub>2</sub>-to-Formate Conversion Over Bi-Polyoxometalate-Derived Catalysts. [PDF]

open access: yesChemistry
Kawakami K   +12 more
europepmc   +1 more source

Dioscin Promotes Ferroptosis in Cervical Cancer Cells via the TIGAR‐ROS Axis

open access: yesCancer Science, EarlyView.
Dioscin suppresses cervical cancer progression by promoting ferroptosis. Mechanistically, Dioscin binds to TIGAR and inhibits TIGAR function, elevating ROS levels and inducing ferroptosis. ABSTRACT Cervical cancer seriously threatens women's life and health, highlighting the urgent need for targeted therapies.
Yameng Liu   +6 more
wiley   +1 more source

High-Performance Thrombin Aptamers with a Peptide-Extended Recognition Interface. [PDF]

open access: yesACS Omega
Varizhuk IV   +6 more
europepmc   +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

open access: yesClinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto   +121 more
wiley   +1 more source

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