Results 231 to 240 of about 69,416 (282)

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

open access: yesChemistry – A European Journal, Volume 32, Issue 41, 3 November 2026.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup   +5 more
wiley   +1 more source

Technical development and implementation of 3D‐QALAS on a 1.5T MR‐Linac for the brain: A prospective R‐IDEAL stage 0/1 technology development report

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Quantitative relaxometry of the brain on the integrated MRI / linear accelerator (MR‐Linac) at high isotropic reconstructed resolution is currently limited due to prohibitively long scan times and limited field‐of‐views. Purpose The purpose of this study was to assess the technical feasibility of the 3D‐QALAS technique on the 1.5T ...
Lucas McCullum   +8 more
wiley   +1 more source

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao   +9 more
wiley   +1 more source

Elevated circulating bile acids driven erythrocyte osmotic resistance marks hepatobiliary disease. [PDF]

open access: yesAm J Physiol Gastrointest Liver Physiol
Yeoh BS   +7 more
europepmc   +1 more source

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