Results 211 to 220 of about 44,793 (291)

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

The FEBS Journal, Volume 293, Issue 11, Page 3288-3302, June 2026.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu Yang   +8 more
wiley   +1 more source

Research on the degradation mechanism, product effects and optimization strategy of the tributyl phosphate solvent system in the PUREX process. [PDF]

Smart Mol
Lan T, Liu J, Liu Y.
europepmc   +1 more source

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Nucleolar organization and divergent transcriptional machinery in Giardia lamblia: Structural insights and implications for drug targeting. [PDF]

Parasites Hosts Dis
Gaona-López C.
europepmc   +1 more source

Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux, William Laine, Patrice Maboudou, Jérôme Kluza, Marie‐Amandine Bonte, Flore Gouel, David Devos, Philippe Marchetti, Jean‐Christophe Devedjian   +8 more
wiley   +1 more source

Heteroaryl derivatives for hole-transport layers improve thermal stability of perovskite solar cells. [PDF]

Nat Commun
Kanda H, Mondal S, Eguchi N, Nishimura N, Hinuma Y, Yamamoto K, Yumoto M, Tashiro K, Takada H, Narazaki A, Koida T, Murakami TN.   +11 more
europepmc   +1 more source

Case Report: A case of refractory tuberculous peritonitis mimicking and complicating suspected encapsulating peritoneal sclerosis in a long-term peritoneal dialysis patient. [PDF]

Front Med (Lausanne)
Cui T, Huang M.
europepmc   +1 more source

Machine learning and response surface analysis of mean drop size and dispersed phase holdup in an L-shaped pulsed sieve plate column. [PDF]

Sci Rep
Ardestani F, Bahmanzadegan F, Ghaemi A.
europepmc   +1 more source

Cooperative clamp-mediated promoter recognition by poxviral RNA polymerase and its TBP/TFIIB-like partner. [PDF]

Nat Commun
Jungwirth S, Bartuli J, Lamer S, Schlosser A, Grimm C, Fischer U.   +5 more
europepmc   +1 more source

Molecular Prevalence and Genetic Characterization of Bovine Tick-Borne Protozoa in Thai and Imported Beef Cattle in Thai-Myanmar Border and Infesting Ticks from Kanchanaburi Province, Thailand. [PDF]

Pathogens
Bhadury P, Do T, Pilean N, Chimnoi W, Kamyingkird K, Xuan X, Inpankaew T.   +6 more
europepmc   +1 more source