Results 101 to 110 of about 180,209 (267)

Engineered TIGIT‐Blockade Membrane Vesicles Synergize with Microwave Ablation to Mediate Liver Metastases Eradication

open access: yesAdvanced Science, EarlyView.
Microwave ablation (MWA) represents a highly effective and clinically significant therapeutic modality for the treatment of liver metastases. This study develops engineered cell membrane vesicles to specifically target the transition zone of MWA for liver metastases. This strategy can inhibit VEGF‐mediated immunosuppression, block CD155/TIGIT signaling
Shaoyue Li   +16 more
wiley   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang   +5 more
wiley   +1 more source

Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville   +6 more
wiley   +1 more source

Multicatalytic Access to Renewable Poly(Silyl Ether)s with Tunable Properties

open access: yesAngewandte Chemie International Edition, EarlyView.
This work presents a one‐pot, multicatalytic approach that combines magnesium‐catalyzed esterification and borane‐mediated hydrosilylation for the synthesis of partially bio‐based poly(silyl ethers). This method allows for the tuning of thermal and mechanical properties, including exceptional extensibility (>3800%), and enables efficient chemical ...
Fan Yang, Fan Sun, Christophe M. Thomas
wiley   +1 more source

Exergy and Economic Analysis of Hybrid Mechanical Vapor Compression and Membrane Distillation

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Hybridization of two or more desalination processes has been identified as an attractive option for improved energy efficiency and recovery rate. To appropriately assess the performance enhancement of hybrid desalination systems, an integrated approach for energy, exergy, economic, and environmental investigations should be adopted. This study
Emad Ali, Jamel Orfi
wiley   +1 more source

Traditional Chinese Medicine Ion Introduction Therapy Reduces the Incidence of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Prospective Cohort Study

open access: yesInternational Journal of General Medicine
Yan Wang,1,2 Baichuan Xu,1,2 Jiajia Wang,1,3,4 Suyun Li,1,3,4 Yang Xie1,3,4 1National Regional Traditional Chinese Medicine (Lung Disease) Diagnosis and Treatment Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou ...
Wang Y, Xu B, Wang J, Li S, Xie Y
doaj  

Transition From Psoriasis to Psoriatic Arthritis is Characterized by Distinct Alterations in Peripheral Blood Tc17, Th17, and CD4+ Effector Memory Cells

open access: yesArthritis &Rheumatology, EarlyView.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff   +19 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

Iterative Detection of Diagonal Block Space Time Trellis Codes, TCM and Reversible Variable Length Codes for Transmission over Rayleigh Fading Channels

open access: yes, 2004
Iterative detection of Diagonal Block Space Time Trellis Codes (DBSTTCs), Trellis Coded Modulation (TCM) and Reversible Variable Length Codes (RVLCs) is proposed.
Guo, F., Hanzo, L., Ng, S. X.
core  

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

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