Results 71 to 80 of about 16,750 (207)

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

open access: yesCell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie   +6 more
wiley   +1 more source

Numerical determination of the exponents controlling the relationship between time, length and temperature in glass-forming liquids

open access: yes, 2009
There is a certain consensus that the very fast growth of the relaxation time $\tau$ occurring in glass-forming liquids on lowering the temperature must be due to the thermally activated rearrangement of correlated regions of growing size.
Alava   +12 more
core   +1 more source

Automodification of N‐terminal serine residues facilitates PARP2 release from DNA

open access: yesThe FEBS Journal, EarlyView.
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar   +6 more
wiley   +1 more source

A Unified Approach for Analysis of Faults in Different Configurations of PV Arrays and Its Impact on Power Grid

open access: yesEnergies, 2019
Fault analysis in photovoltaic (PV) arrays is considered important for improving the safety and efficiency of a PV system. Faults do not only reduce efficiency but are also detrimental to the life span of a system.
Saba Gul   +4 more
doaj   +1 more source

Suppression of Indoleamine 2,3‐Dioxygenase Enhances Immune Responses to the Therapeutic Vaccine for Chronic Hepatitis B

open access: yesHepatology Research, EarlyView.
Indoleamine 2,3‐dioxygenase (IDO) activity modulates immune responses to the therapeutic HBV vaccine NASVAC. Genetic or pharmacological suppression of IDO enhanced vaccine efficacy in mice, and lower serum kynurenine levels predicted favorable responses in humans, suggesting IDO as both a therapeutic target and a biomarker.
Yohei Shirakami   +15 more
wiley   +1 more source

The processing peptidase of yeast mitochondria [PDF]

open access: yes, 1988
Two proteins co-operate in the proteolytic cleavage of mitochondrial precursor proteins: the mitochondrial processing peptidase (MPP) and the processing enhancing protein (PEP).
Cheng, Ming Yuan   +5 more
core  

A new catfish species of Microcambeva Costa & Bockmann, 1994 (Siluriformes: Trichomycteridae) from southern Brazil, with a redescription of M. ribeirae Costa, Lima & Bizerril, 2004

open access: yesJournal of Fish Biology, EarlyView.
Abstract Among the few species of Microcambeva reported as occurring in more than one hydrographic basin, M. ribeirae has been previously listed from both the Ribeira de Iguape and the Guaraqueçaba basins. However, morphological and molecular analyses revealed that the specimens from Guaraqueçaba represent a new species, which is described in this ...
Lucas S. de Medeiros   +6 more
wiley   +1 more source

A Novel Reverse Combination Configuration to Reduce Mismatch Loss for Stratospheric Airship Photovoltaic Arrays

open access: yesApplied Sciences
Enhancing the output power of stratospheric airship photovoltaic arrays during months with weak irradiance is crucial for extending the endurance of airships.
Chuan Shan   +5 more
doaj   +1 more source

Intelligent redundant actuation system requirements and preliminary system design [PDF]

open access: yes
Several redundant actuation system configurations were designed and demonstrated to satisfy the stringent operational requirements of advanced flight control systems.
Defeo, P., Geiger, L. J., Harris, J.
core   +1 more source

The cosmic QCD phase transition with dense matter and its gravitational waves from holography

open access: yes, 2018
Consistent with cosmological constraints, there are scenarios with the large lepton asymmetry which can lead to the finite baryochemical potential at the cosmic QCD phase transition scale. In this paper, we investigate this possibility in the holographic
Ahmadvand, M., Fadafan, K. Bitaghsir
core   +1 more source

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