Results 91 to 100 of about 17,625 (217)

Generative Artificial Intelligence in education: Models, Frameworks and the proposal for a new vertical K‐12 Digital Curriculum

The Curriculum Journal, Volume 37, Issue 3, Page 808-831, September 2026.
Abstract This contribution critically analyses the main international educational frameworks for teachers' digital competence, highlighting both critical issues and potential in relation to their professional development and the need to update school curricula.
Daniela Marzano, Roberto Maniglio, Antonella Senese, Guglielmina Diolaiuti   +3 more
wiley   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 196-219, September 2026.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang, Xing Wu, Maria Moreno, Joonseok Oh, Stephen L. Dellaporta, Jason M. Crawford, Farren J. Isaacs   +6 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression: A Systematic Review and Meta‐Analysis of Treatment Response and Suicidal Ideation Reduction

Acta Psychiatrica Scandinavica, Volume 154, Issue 3, Page 187-202, September 2026.
ABSTRACT Introduction Major depressive disorder (MDD) affects 11%–19% of adolescents globally. Early treatment is vital, but the risk of relapse is high, with 46% relapse within 5 years, which threatens a chronic course. Hence, better solutions are needed.
Lidija Rakic, Floris Tas, Miao Chen, Indira Tendolkar, Philip van Eijndhoven, Jozarni Dlabac‐de Lange, Mieke Klein Hofmeijer, Adriaan Hoogendoorn, Didi Rhebergen   +8 more
wiley   +1 more source

NLRC5‐Deficient Macrophages Promote a Tumor‐Permissive Phenotype via AXL‐ and MERTK‐Mediated Efferocytosis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Defective NLRC5 signaling in macrophages drives TAM phenotype and anti‐inflammatory responses via STAT3/ERK, leading to tumor‐permissive conditions and gastric lymphoid neogenesis during Helicobacter infection. ABSTRACT The innate immune protein NLRC5 plays a key role in cancer immune surveillance.
Shambel Araya Haile, Alessandra Gatta, Nina Colon, Dana J. Philpott, Thomas A. Kufer, Le Ying, Dongmei Tong, Richard L. Ferrero   +7 more
wiley   +1 more source

Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening

Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker, Meghan E. Campbell, Peyton M. Higgins, Andrew R. Buller   +3 more
wiley   +2 more sources

Transcranial direct current stimulation (tDCS) research in Indian psychiatry: A bibliometric analysis

Indian Journal of Psychiatry
Background: There has been a consistent increase in the use of transcranial direct current stimulation (tDCS) in psychiatric practice and academic research in India.
Ilambaridhi Balasubramanian, Ragul Ganesh   +1 more
doaj   +1 more source

Non‐Contiguous Double Thyroglossal Duct Cysts: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Thyroglossal duct cysts (TDCs) are conventionally considered solitary lesions connected to a persistent embryological tract. While rare double TDCs have been reported, they are almost invariably anatomically continuous. We report a paradigm‐shifting case of non‐contiguous double TDCs in a 50‐year‐old male, featuring two anatomically discrete ...
Baogang Wang, Bo Sun, Shujun Li, Lurong Han   +3 more
wiley   +1 more source

Development and Genetic Monitoring of a Putatively Thiamine Deficiency Complex Tolerant Atlantic Salmon Broodstock

Ecology and Evolution, Volume 16, Issue 8, August 2026.
We introduce efforts to develop a potentially thiamine deficiency complex (TDC) tolerant Atlantic salmon broodstock via selective breeding, as well as control broodstock with higher genetic diversity (and no selection). Additionally, we develop the genetic monitoring tools (novel genetic marker panel, parentage‐based tagging) to monitor the demographic
Kurt C. Heim, Avril M. Harder, Laurie A. Earley, Paul Boynton, Shane Hanlon, Jacques Rinchard, Kevin Kelsey, Stacey A. Nerkowski, Nathan R. Campbell, William R. Ardren   +9 more
wiley   +1 more source

ASK1‐Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice

Obesity, Volume 34, Issue 8, Page 1635-1646, August 2026.
ABSTRACT Objective Fibroblast growth factor 21 (FGF21) is a stress‐induced hormone secreted by the liver. It has a beneficial role in the regulation of glucose and energy metabolism. Herein, we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 synthesis.
Anne Goergen, Tenagne D. Challa, Carlos Villaroel‐Vicente, Marcela Borsigova, Pim P. van Krieken, Christian Wolfrum, Matthias Blüher, Stephan Wueest, Daniel Konrad   +8 more
wiley   +1 more source