Results 191 to 200 of about 18,374 (246)

Advancing laboratory animal science in the Philippines: PALAS initiatives and partnerships leading to Asia Laboratory Animal Day 2025

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract As the Philippines celebrated the 2nd Asia Laboratory Animal Day (ALAD) last November 29, 2025, the Philippine Association for Laboratory Animal Sciences (PALAS) reflected on a year marked by growth, collaboration, and renewed commitment to ethical and scientific excellence in animal‐based research.
Rodel Jonathan S. Vitor II   +10 more
wiley   +1 more source

Malaysia's commemorative activities for the second Asia Laboratory Animal Day (ALAD)

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Summary of Malaysia's ALAD 2025 initiatives, activities, institutional collaboration, and outcomes in strengthening ethical laboratory animal research and technical competency. Abstract Malaysia's commemoration of the second Asia Laboratory Animal Day (ALAD) in 2025 marked a notable step forward in strengthening national and regional laboratory animal ...
John Shia Kwong Siew
wiley   +1 more source

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

open access: yesAngewandte Chemie, EarlyView.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde   +11 more
wiley   +2 more sources

Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia

open access: yesAnnals of Neurology, EarlyView.
Objective Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair‐bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract.
Anna‐Sophie Hofer   +21 more
wiley   +1 more source

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

open access: yesAngewandte Chemie, EarlyView.
Nonheme Fe enzyme isopenicillin N synthase was reprogrammed and evolved as an efficient nitrogen migratase IPNSNim, converting diverse azanyl esters to valuable l‐arylglycines with up to 16 000 TTN and 97:3 e.r. IPNSNim and ACCONim allowed enantiodivergent preparation of both l‐ and d‐arylglycines.
Ken Lin   +7 more
wiley   +2 more sources

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