PIVOT uses pathology‐derived morphologic and vascular representations from postoperative H&E and CD34 whole‐slide images to guide model development, while clinical inference requires only preoperative multiparametric MRI. Across five centers, PIVOT enabled accurate preoperative assessment of vessels encapsulating tumor clusters, stratified patients by ...
Zhehan Shen +12 more
wiley +1 more source
Orff Schulwerk in Chinese primary music classrooms: a qualitative study of teachers' teaching self-efficacy and work engagement. [PDF]
Ge S, Li M.
europepmc +1 more source
ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu +11 more
wiley +1 more source
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Changes in Oral Health Knowledge, Beliefs, and Self-Reported Practices Among Preschool Teachers Between 3 and 12 Months After School-Based Education. [PDF]
Koc G, Baygin O.
europepmc +1 more source
LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
Metacognitive training and AI-based Socratic scaffolding in pre-service teachers' reflective practice: a dual-study experimental design. [PDF]
Zhang WL +5 more
europepmc +1 more source
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu +8 more
wiley +1 more source
From Artificial to Embodied and Physical Intelligence in Smart Manufacturing
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang +9 more
wiley +1 more source
Transformational Leadership and Heterogeneity in Teachers' Readiness for AI Integration: A Complementary Variable- and Person-Centered Approach. [PDF]
Geng Y, Geng K, Wang K, Ruan Q.
europepmc +1 more source

