Results 221 to 230 of about 5,446,945 (286)

An AI‐Driven Framework for Directed Self‐Assembly Toward Design‐Technology Co‐Optimization

open access: yesAdvanced Science, EarlyView.
An artificial intelligence (AI)‐driven closed‐loop framework integrates experiment, three‐dimensional physics‐based simulation, and template design for directed self‐assembly (DSA). Guided by experimental data, AI‐assisted calibration accelerates model optimization, supports morphology prediction, and identifies template windows.
Caiwei Shang   +9 more
wiley   +1 more source

Histone Lactylation Drives WNK1 Expression to Promote Esophageal Squamous Cell Carcinoma Progression Through Histone H3 Ser10 Phosphorylation

open access: yesAdvanced Science, EarlyView.
In brief. Yan et al. demonstrated that the excess lactate produced by the enhanced glycolysis pathway in esophageal cancer can lactylate H3K23, H3K23la can be enriched in the WNK1 promoter region to promote WNK1 expression, thereby increasing the phosphorylation of the p‐H3 Ser10 site, and p‐H3S10 can be enriched in the AKT1 promoter region to promote ...
Mingyang Yan   +12 more
wiley   +1 more source

A CT Lesion Foundation Model for Non‐Invasive Assessment of Hepatocellular Carcinoma Aggressiveness and Prediction of Recurrence Risk

open access: yesAdvanced Science, EarlyView.
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia   +9 more
wiley   +1 more source

AI‐Assisted Ultrasensitive Biosensing using Metal‐Electrolyte‐Metal‐Insulator‐Silicon Structure Based on Oxygen‐Tunable Iridium Oxide Nanonets for Lysyl‐Oxidase‐Like‐2 Breast Cancer Detection

open access: yesAdvanced Electronic Materials, EarlyView.
An oxygen‐controlled iridium‐oxide (IrOx) nano‐net structure is developed to enhance the sensitivity of metal‐electrolyte‐metal‐insulator‐silicon (MEMIS) biosensors. Integrated with a deep learning model, this platform achieves a high accuracy of 94.8% for detecting the breast cancer biomarker LOXL2.
Chiao‐Fan Chiu   +9 more
wiley   +1 more source

Extension Economists: Valued in Mission, Penalized in Practice

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT As the public engagement arm of the land‐grant mission, we argue that Extension faculty in US agricultural economics departments face an identity crossroads as they struggle for institutional support. Specifically, we argue that Extension economists function as boundary‐spanning professionals within academic structures that often devalue ...
Trey Malone   +5 more
wiley   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

open access: yesAgribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn   +3 more
wiley   +1 more source

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