Results 131 to 140 of about 3,794,363 (398)
The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp+5 more
wiley +1 more source
Our research aimed to optimize the oil extraction process and determine the fatty acids in Brucea javanica (L.) Merr. seeds. The extraction technology was optimized using response surface methodology.
Zhuona Wu+7 more
doaj +1 more source
The Teaching and Learning of Psychotherapy.
Modern psychiatry is at present involved in perfecting and discriminating various psychotherapeutic techniques. There are many studies now supported with adequate funds that are oriented toward understanding the therapeutic relationships that offer ...
R. Grinker
semanticscholar +1 more source
Dipping Into the Weekly Reader Mailbag: You Have Questions? We Have Answers! [PDF]
https://digitalcommons.winthrop.edu/weeklyreader/1042/thumbnail ...
Bird, John, Teaching and Learning Center
core +1 more source
State of the Art of Low‐Frequency Acoustic Modulation: Intensity Enhancement and Directional Control
High intensity low‐frequency sound sources hold significant value in many fields. However, their long wavelength, strong penetrability, and tendency to diffract make direction control and intensity enhancement challenging. Acoustic generators and metamaterial‐based acoustic devices still face issues such as low energy efficiency, poor directional ...
Jingsong Xu+13 more
wiley +1 more source
Beyond Participatory Design: Towards a Model for Teaching Seniors Application Design [PDF]
Population aging and the ubiquity of technology in everyday life have made designing solutions for older adults a necessity. User-centered and participatory design approaches include elderly users in the software development process to some extent but do not encourage them to take a leading role in designing applications to address their unmet needs ...
arxiv
Warnings From the Trenches - But I Thought We Were in the Trenches! [PDF]
https://digitalcommons.winthrop.edu/weeklyreader/1019/thumbnail ...
Bird, John, Teaching and Learning Center
core +1 more source
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du+12 more
wiley +1 more source
Guest Column: College Students and Stress: What Can We Do to Help? [PDF]
https://digitalcommons.winthrop.edu/weeklyreader/1094/thumbnail ...
Hamill, Shelley+1 more
core +1 more source
There is growing interest in understanding how classroom teaching works, but previous theories and studies leave a gap in the neurocognitive mechanisms involved in real classroom teaching. Here we show that during real classroom teaching, students' middle frontal cortex serves as a hub of a rapid cortical learning process, supporting their knowledge ...
Xiaodan Feng+6 more
wiley +1 more source