Results 181 to 190 of about 1,163,868 (343)

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

open access: yesAdvanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei   +13 more
wiley   +1 more source

Teaching Naked: Part Two [PDF]

open access: yes, 2013
https://digitalcommons.winthrop.edu/weeklyreader/1022/thumbnail ...
Bird, John, Teaching and Learning Center
core   +1 more source

Advanced Brain‐on‐a‐Chip for Wetware Computing: A Review

open access: yesAdvanced Science, EarlyView.
Exploring Low‐Power, Beyond‐Silicon‐Computing Bio‐Computing: Brain‐on‐a‐Chip Technology. This article reviews the applications of Brain‐on‐a‐Chip in Wetware Computing, including in vitro‐cultured brain organoids, microelectrode arrays, electrophysiological interfaces, and microfluidic platforms, as well as data processing methods. It also looks forward
Shangchen Li   +11 more
wiley   +1 more source

Pedagogy First, Technology Second The Do’s and Don’ts of Teaching with Technology [PDF]

open access: yes, 2002
The Center for Learning and Teaching at AUC has just launched a pilot program (Student Technology Assistants Program) aimed at helping faculty with matters of instructional technology.
Center for Learning and Teaching, The
core   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

open access: yesAdvanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai   +13 more
wiley   +1 more source

2014 Faculty Conference: teaching and innovative learning center

open access: yes, 2007
This presentation outlines the development of a teaching and innovative learning center, including the impetus for its creation, the roles it will fill and functions it will provide, and a timeframe for its progress.
openaire   +3 more sources

Home - About - Disclaimer - Privacy