Results 141 to 150 of about 1,284,800 (290)

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Cohort Turnover and Productivity: The July Phenomenon in Teaching Hospitals [PDF]

The impact of labor turnover on productivity has received a great deal of attention in the literature on organizations. We consider the impact of cohort turnover -- the simultaneous exit of a large number of experienced employees and a similarly sized ...
Jason Barro, Robert S. Huckman
core  

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi, Sunghoon Lee, Tomoyuki Yokota, Takao Someya   +3 more
wiley   +1 more source

Evaluation of Human Resource Productivity Dimensions Based on ACHIEVE Model: a study on personnel of hospitals affiliated to Iran University of Medical Sciences

پژوهش‌های سلامت‌محور, 2019
Evaluation of Human Resource Productivity Dimensions Based on ACHIEVE Model: a study on personnel of hospitals affiliated to Iran University of Medical Sciences Jafari Mehdi1, Hedayatirad Sedigheh2*, Aryankhesal Aidin3, Bordbar Najmeh4, Tavakoli Nader5
Mehdi Jafari, Sedigheh Hedayati rad, Aidin Aryankhesal, Najmeh Bordbar, Nader Tavakoli   +4 more
doaj  

Healthcare and Teaching Hospitals [PDF]

Revista da Associação Médica Brasileira, 2018
Olímpio J. Nogueira V. Bittar, José Dínio Vaz Mendes   +1 more
openaire   +2 more sources

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Patient Satisfaction With Medication Pricing in Community Pharmacy Settings: A Cross‐Sectional Study of Individuals With Comorbidities

AGING MEDICINE, EarlyView.
The majority of patients in Malaysia purchase medications at community pharmacies for simple medical conditions. One‐fourth of them are not satisfied with the pricing practices at these pharmacies. The majority rely on medical insurance to purchase routine medications.
Amelia Ravindran, Palanisamy Sivanandy, Sajesh Kalkandi Veettil, Priya Manirajan   +3 more
wiley   +1 more source

EQUINE REFERRING VETERINARIAN SATISFACTION WITH THE VETERINARY TEACHING HOSPITAL, MICHIGAN STATE UNIVERSITY - JULY 1, 1999 THROUGH JUNE 30, 2000 [PDF]

Understanding clients' wants and needs is vital to the sustained success of any service business, and veterinary medicine offers no exception. The Veterinary Teaching Hospital (VTH) at the Michigan State University College of Veterinary Medicine (MSU-CVM)
Camara, Youssouf, Donovan, Debra, Gross, Renee, Leeper, Delta, Lloyd, James W.   +4 more
core   +1 more source

Construction of a Feedback Comment Analysis Model for Evaluation of Endoscopic Surgical Skill

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical education and skill assessments are important in improving surgical skills. However, instructors' comments tend to be complex and unorganized, with varying content and categories. This study aimed to develop a natural language processing (NLP) model to automatically classify feedback comments on surgical procedures and ...
Shusaku Iwai, Shin Takenaka, Daichi Kitaguchi, Hiroki Matsuzaki, Kei Nakajima, Yuya Takabe, Nobuyoshi Takeshita, Masaaki Ito   +7 more
wiley   +1 more source