Results 51 to 60 of about 2,823,823 (297)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Mathematics and science education with teaching methods: mathematics with teaching methods. Natural education with teaching methods [PDF]
, 2019 У робочій навчальній програмі подано мету, зміст та завдання вивчення дисципліни "Математика і природнича освіта з методикою навчання: математика з методикою навчання.
Романенко, Катерина Анатоліївна +1 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
فاعلية برنامج قائم على القصص الرقمية في تنمية مهارات التعبير الشفوي لدى تلميذات الصف الرابع الأساسي
دراسات: العلوم التربوية, 2023 الأهداف: هدفت الدراسة إلى التعرف على فاعلية برنامج قائم على القصص الرقمية في تنمية مهارات التعبير الشفوي لدى تلميذات الصف الرابع الأساسي. المنهجية: لتحقيق أهداف الدراسة اتبع الباحثان المنهج التجريبي، حيث اختيرت العينة بطريقة عشوائية، وقد تكونت عينة ...
Adham Hasan Al Baloji +1 more
doaj
A MODERN COMPREHENSIVE COURSE AT SCHOOL AND UNIVERSITY: APPROACHES TO THE CONTENT DEVELOPMENT
Открытое образование (Москва), 2016 The article considers the problem of the development of modern computer science curriculum that reflects the modern paradigm of science informatics and new educational trends, where a significant place is given to the formation of the trainees have the ...
Eteri V. Mindzaeva, Sergey A. Beshenkov
doaj +1 more source
Teaching writing for high-stakes exams using communicative language teaching methods [PDF]
, 2013 Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Rockenhaus, Melanie
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Pharmacy Students Learning Styles and Preferences toward Teaching Methods in Learning Pharmaceutical Care Concept [PDF]
, 2011 The paradigm concerning the role of pharmacist has shifted from supplying drugs to providing pharmaceutical care services.1 Pharmacy faculties have responsibility to develop a curriculum that enables pharmacy students to provide pharmaceutical care ...
Hadisaputro, Dewi P., Irawati, Sylvi
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Teaching and learning in information retrieval [PDF]
, 2009 A literature review of pedagogical methods for teaching and learning information retrieval is presented. From the analysis of the literature a taxonomy was built and it is used to structure the paper.
Efthimiadis, E. N. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source