Results 31 to 40 of about 633,426 (313)

The Experience of Teaching Creative Practices: Conceptions and Approaches to Teaching in the Community of Practice Dimension [PDF]

open access: yes, 2004
This paper explores conceptions and approaches to teaching held by academics in departments of art, design and communication and explores links between the conceptions, the approaches and the communities of practice associated with the subject context ...
Drew, Linda
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Teaching, Practice and Technology [PDF]

open access: yesAmerican Journal of Pharmaceutical Education, 2007
I continue to be amazed at the advancements in the technologies we can use daily to transfer and share information with our students and with each other for our various teaching, scholarly, and service activities. We are continuously bombarded by voice mail, e-mail, instant messaging, text messaging, and pod casts throughout each day. It seems to never
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Leukopenia and thrombocytopenia in dengue patients presenting in the emergency department of a tertiary center in Nepal: a cross-sectional study

open access: yesBMC Infectious Diseases
Introduction Dengue viruses cause either symptomatic infections or asymptomatic seroconversion. Symptomatic dengue has a wide clinical spectrum ranging from self-limiting infection to severe manifestations, mostly characterized by plasma leakage with or ...
Bibechan Thapa   +7 more
doaj   +1 more source

Association between family support and 6-months functional recovery in acute ischemic stroke patients: a prospective cohort study

open access: yesFrontiers in Medicine
AimsStroke is a leading cause of disability and death worldwide, with family support playing a pivotal role in the recovery process. This study aimed to evaluate the association between family support levels and the short-term functional prognosis of ...
Ming Zhong   +10 more
doaj   +1 more source

Hospital admissions for stress-related presentations among school-aged adolescents during term time versus holidays in England: weekly time series and retrospective cross-sectional analysis

open access: yesBJPsych Open, 2021
Background Schools are a potential stressor for adolescents and may contribute to emergency hospital admissions. Aims We describe rates of stress-related presentations (SRPs) among school-aged adolescents (11–17 years) during school terms and holidays,
Ruth Blackburn   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Acute Poisoning among Patients Presenting to the Emergency Department of a Tertiary Care Center: A Descriptive Cross-sectional Study

open access: yesJournal of Nepal Medical Association, 2020
Introduction: Acute poisoning is a major global public health problem contributing to one of the leading causes for a visit to an emergency department.
Sameer Thapa   +2 more
doaj   +1 more source

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