Results 71 to 80 of about 6,165,116 (328)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Applying theory to practice in a large research center: creating and implementing tools for building convergence capacity in individuals and teams

open access: yesFrontiers in Psychology
The continued expansion of team science underscores the urgent need for shared, actionable models that can be validated to support effective interdisciplinary collaboration in scientific teams.
Kimberly Bourne   +6 more
doaj   +1 more source

Crafting better team climate: the benefits of using creative methods during team initiation [PDF]

open access: yes, 2019
This study employs a mixed methods approach to investigate the effect of creative methods, the combinative use of model building and storytelling, during team initiation on team climate, a critical people-related factor in the management of collective ...
Jiang, Crystal, Primus, Dirk
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Medical students as EMTs: skill building, confidence and professional formation [PDF]

open access: yesMedical Education Online, 2014
Objective: The first course of the medical curriculum at the Hofstra North Shore-LIJ School of Medicine, From the Person to the Professional: Challenges, Privileges and Responsibilities, provides an innovative early clinical immersion. The course content
Thomas Kwiatkowski   +3 more
doaj   +1 more source

The Task of a Project Manager in Building Individual and Project Team Capability in Modern Day Project Work [PDF]

open access: yes, 2017
From the point of view of an organization, projects act as a means for consolidating the experience and expertise of the organizational members effectively, create learning environment, encourage team-spirit and help to achieve organizational objectives.
Ackah, David   +2 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

A case study on autonomous team-building in healthcare

open access: yesJournal of Human Environmental Studies, 2007
The purpose of this paper is to consider whether healthcare teams (or medical teams) can address autonomous team-building. The work of healthcare organizations is being carried out by teams and groups, it is inevitable that healthcare workers, such as ...
Chiaki Kusano
doaj   +1 more source

Advice to a New Child Services Leader [PDF]

open access: yes, 2011
Offers advice to new leaders of child services agencies in the areas of leadership, administration, communication, and data. Discusses developing a strategy for change, building a management team, working with the media, and measuring ...
James W. Payne
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

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