Results 51 to 60 of about 15,099,737 (280)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Association of serum 25-hydroxyvitamin D concentrations with Schirmer tear test 1 and tear film breakup time in dogs

Journal of Veterinary Science, 2023
The association between vitamin D and canine keratoconjunctivitis sicca (KCS) has not been investigated in dogs.To investigate the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with Schirmer tear test 1 (STT-1) and tear film breakup time (TFBUT) in dogs.Sixty-one clinically healthy, client-owned dogs were enrolled.
Youngsam Kim, Seonmi Kang, Kangmoon Seo
openaire   +2 more sources

Tear film parameters in females with thyroid eye disease and diabetes: an observational study

Journal of the Pakistan Medical Association
Objective: To assess different tear film parameters in female patients with thyroid eye disease and diabetes using a single portable device. Method: The observational study was conducted at the College of Applied Medical Sciences, King Saud University,
Mana Alafri Alanazi, Amaal Almutairi, Alanoud Abdulaziz Al-Massaad, Mashaaer Abdulwahhab Baashen, Meznah Saud Almutairi, Abdulaziz Alhssan, Gamal Abdel-Rahman El-Hiti   +6 more
doaj   +1 more source

The effect of fluorescein, EDTA, and thimerosal on the rate of tear breakup in man [PDF]

, 1978
This study was undertaken to determine what effect if any that fluorescein, thimerosal, or EDTA would have on tear breakup time. It was found that fluorescein would significantly reduce tear breakup time in man.
Hadlock, Brent L
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Assessment of Wavefront Aberrations in Children with Myopia Against the Background of Ocular Surface Disorders in Combination with Computer Vision Syndrome Digital and Eye Strain

Oftalʹmologiâ
Purpose: to assess the state of the wavefront in children with myopia, who have various manifestations of digital eye strain and symptoms of ocular surface disorders, and to evaluate the diagnostic significance of wavefront criteria for assessing the ...
I. L. Plisov, E. M. Naumova, A. I. Smoleva   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Tear Film Break-up Time in Bipolar Disorder

Iranian Journal of Psychiatry, 2012
Objective: Ocular dryness is a well-recognized adverse side effect of many topical and systemic medications. In psychiatry, patients who have consumed such drugs as lithium carbonate and sodium valproate frequently experience dry eye symptoms.
Maryam Moghadasin, Mohadeseh Mohammadinia, Mohammad Aghazade Amiri, Parvin Dibajnia   +3 more
doaj   +2 more sources

Tear film breakup time (B.U.T.) in sub clinical dry eyes

Indian Journal of Ophthalmology, 1984
Kulshrestha O, Talwar Puspa, Mathur Madhu   +2 more
doaj   +2 more sources