Results 71 to 80 of about 15,099,737 (280)

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Evaluation of tear film breakup time, Schirmer tear test, blink rate and tear ferning test in Shih-Tzu dogs

, 2023
Abstract Background: Shih-Tzu dogs are severely affected by lacrimal surface ophthalmic disorders, such as Dry Eye Disease (DED). The objective of this study was to evaluate tear quality in Shih-Tzu dogs. Thirty dogs underwent eyelid blink counting, tear film breakup time (TBUT) test, Schirmer tear test (STT-1), and tear ferning test (TFT ...
Rebeca Costa Vitor, Jamille Bispo de Carvalho Teixeira, Katharine Costa dos Santos, Gabriela Mota Sena Oliveira, Paula Elisa Brandão Guedes, Anaiá da Paixão Sevá, Deusdete Conceição Gomes Junior, Jéssica Fontes Veloso, Renata Santiago Alberto Carlos   +8 more
openaire   +1 more source

Evaluation of minor labial salivary gland transplantation for treatment of dry eye in brachycephalic breeds of dogs* [PDF]

Journal of Veterinary and Animal Sciences, 2020
Six brachycephalic breeds of dogs irrespective of age and sex presented to the Teaching Veterinary Clinical Complex, Mannuthy, and University Veterinary Hospital, Kokkalai, were selected for treatment of dry eye condition.
T. Karthikaa, C. B. Devanand, S. Anoop, S. Sudheesh Nair, K.B. Sumena, K.M. Dileep kumar   +5 more
doaj  

Flexural Behavior of 3D‐Printed Porous Bouligand‐Structured Polymers: Influence of Pitch Angle and Porosity

Advanced Engineering Materials, EarlyView.
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil, Edward D. McCarthy, Parvez Alam   +2 more
wiley   +1 more source

A fully automated dry eye and breakup pattern detection based on deep learning

Journal of King Saud University: Computer and Information Sciences
Dry Eye Disease (DED) is a chronic ocular condition characterized by a high prevalence rate. It arises from an imbalance between tear secretion and the evaporation of the tear film’s aqueous component, leading to tear film instability.
Gengyuan Wang, Peng Xiao, Yuancong Huang, Jin Yuan   +3 more
doaj   +1 more source

Tear Osmolarity, Break-up Time and Schirmer’s Scores in Parkinson’s Disease

Türk Oftalmoloji Dergisi, 2015
Objectives: Dry eye is an important problem in Parkinson’s disease (PD) with a potential to affect life quality. Tear osmolarity, accepted as the gold standard in dry eye diagnosis, has not been studied in this subset of patients so far.
Esin Söğütlü Sarı, Rabia Koç, Alper Yazıcı, Gözde Şahin, Harun Çakmak, Tolga Kocatürk, Sıtkı Samet Ermiş   +6 more
doaj   +1 more source

Inverse Identification of Energy‐Dependent Laser Absorptivity in NiTi Laser Powder‐Bed Fusion via Calibrated Melt Pool Simulation

Advanced Engineering Materials, EarlyView.
A combined experimental–computational framework identifies energy‐dependent laser absorptivity for NiTi in laser powder‐bed fusion, applicable to conduction and transition modes. Single‐track experiments and thermofluid smoothed particle hydrodynamics simulations are coupled through inverse analysis of melt pool geometry.
Mohamadreza Afrasiabi, Hadi Moutablaleh, Ignatius A. Setiawan, Mehrshad Mehrpouya   +3 more
wiley   +1 more source

Tear-film breakup: the role of membrane-associated mucin polymers

, 2019
with Mohar Dey and Xiaoyang Xu The tear film has a heterogeneous structure. Next to the ocular surface is a region hundreds of nanometers thick that is rich in mucin polymers.
Feng, James J.
core   +1 more source

Temporary Dry Eyes Caused by Eating Fried Foods

Engineering Proceedings
Tear osmotic pressure, tear volume, and quality were measured before and after subjects without dry eye syndrome ate fried chicken slices for one week. By analyzing the data, we explored the causes of temporary dry eye syndrome.
Yung-Fu Liu, Feng-Ming Yeh, Ya-Hui Hsieh, Cheng-Hung Lai, Wei-Hsin Chen, Der-Chin Chen   +5 more
doaj   +1 more source