Results 41 to 50 of about 1,517,602 (292)

Extensive characterization of human tear fluid collected using different techniques unravels the presence of novel lipid amphiphiles1[S]

Journal of Lipid Research, 2014
The tear film covers the anterior eye and the precise balance of its various constituting components is critical for maintaining ocular health. The composition of the tear film amphiphilic lipid sublayer, in particular, has largely remained a matter of ...
Sin Man Lam, Louis Tong, Xinrui Duan, Andrea Petznick, Markus R. Wenk, Guanghou Shui   +5 more
doaj   +1 more source

Giving the Side-Eye: Asymmetrical Response of the Tear Film Margins to Lateral Gaze Changes

Journal of Clinical & Translational Ophthalmology
Background: Lateral eye movements are part of natural ocular motility, and their effect on tear film behavior is largely unknown because they are usually not evaluated during tear film examinations, where patients are required to look straight ahead ...
Timon Ax, Fabian N. Fries, Tomas L. Bothe, Francesc March de Ribot, Slade O. Jensen, Thomas J. Millar, Berthold Seitz   +6 more
doaj   +1 more source

Dynamics of tear film deposition and draining

, 2005
This paper investigates the deposition of the tear film on the cornea of the human eye. The tear film is laid down by the motion of the upper eyelid and then subsequently flows and thins.
Jones, M.B., Fulford, G. R., Roberts, G.R., Roberts, A. P., Fulford, D.L.S., Please, C. P., McElwain, D. L. S., Fulford, G., Jones, M. B., McElwain, M.B., Collins, M. J., Please, C.P., Collins, A.P.   +12 more
core   +1 more source

Biological functions of tear film

Experimental Eye Research, 2020
Tears have a vital function to protect and lubricate the ocular surface. Tear production, distribution and clearance is tightly regulated by the lacrimal functional unit (LFU) to meet ocular surface demands. The tear film consists of an aqueous-mucin layer, containing fluid and soluble factors produced by the lacrimal glands and mucin secreted by the ...
Stephen C, Pflugfelder, Michael E, Stern
openaire   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Instrument for simultaneous assessment of fluorescein and thermal dynamics of the tear film [PDF]

, 2017
Ocular thermography has been identified as a potential technique for non-invasive assessment of various tear-film disorders, particularly dry eye. \ud \ud Using infrared thermal imaging, past studies have shown that changes in ocular surface temperature (
Alonso-Caneiro, David, McNeill, Hamish, Titze, Michael, Kricancic, Henry, Collins, Michael J.   +4 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

An imaging system integrating optical coherence tomography and interferometry for in vivo measurement of the thickness and dynamics of the tear film

BioMedical Engineering OnLine, 2018
Background The outermost layer of the tear film consists of a thin lipid layer (LL). The lipid layer serves as a barrier against evaporation of the aqueous component of the tear film. The ability to simultaneously image both the lipid layer thickness and
Yuqiang Bai, William Ngo, Boyu Gu, Yuhua Zhang, Jason J. Nichols   +4 more
doaj   +1 more source

Tear and Saliva Metabolomics in Evaporative Dry Eye Disease in Females

Metabolites, 2023
Accurate diagnosis of dry eye disease (DED) is challenging, and even today there is no gold standard biomarker of DED. Hypothesis-free global metabolomic studies of tears from DED patients have great potential to discover metabolites and pathways ...
Fredrik A. Fineide, Behzod Tashbayev, Katja B. P. Elgstøen, Elise M. Sandås, Helge Rootwelt, Håvard Hynne, Xiangjun Chen, Sten Ræder, Jelle Vehof, Darlene Dartt, Janicke L. Jensen, Tor P. Utheim   +11 more
doaj   +1 more source

Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis

, 2015
Objectives: To investigate the tear film osmolarity in eyes with chronic blepharitis. Materials and Methods: Patients with symptomatic chronic blepharitis were included in the study. After ophthalmologic examination, tear osmolarity was measured.
Şule Ziylan, Ferda Çiftçi, YENEREL, NURSEL MELDA, Ebru Görgün, ZİYLAN, ŞULE, Canan Aslı Utine, KÜÇÜMEN, RACİHA BERİL, Raciha Beril Küçümen, Nursal Melda Yenerel, YILDIRIM, CANAN ASLI, ÇİFTÇİ, FERDA, GÖRGÜN, EBRU   +11 more
core   +1 more source