Results 51 to 60 of about 1,517,602 (292)

Evaporation-driven instability of the precorneal tear film [PDF]

open access: yes, 2018
Tear-film instability is widely believed to be a signature of eye health. When an interblink is prolonged, randomly distributed ruptures occur in the tear film. "Black spots" and/or "black streaks" appear in 15 to 40 s for normal individuals.
Braun, Richard J   +3 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

The Effect of Prolactinoma on Tear Film Function

open access: yes, 2022
Objectives:To compare dry eye parameters in prolactinoma patients and healthy controls and evaluate their correlation with prolactin (PRL) levels and the duration of hyperprolactinemia.Materials and Methods:Consecutive patients with prolactinoma and ...
Cezmi Doğan   +11 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Tear film lipid layer increase after diquafosol instillation in dry eye patients with meibomian gland dysfunction: a randomized clinical study

open access: yesScientific Reports, 2019
Diquafosol promotes secretion of tear fluid and mucin at the ocular surface and is administered for treatment of dry eye (DE). Tear film lipid layer is secreted from meibomian glands and stabilizes the tear film.
Shima Fukuoka, Reiko Arita
doaj   +1 more source

Preocular Tear Film Tests in Acute Hemorrhagic Conjunctivitis Caused by Coxsackievirus A24 Variant

open access: yes, 2012
Pur po se: Our aim was to evaluate the preocular tear film in patients who had acute hemorrhagic conjunctivitis (AHC) caused by coxsackievirus A24 variant (CVA24v).
Evre Pekel   +6 more
core   +1 more source

Impact of MgO Additions on the Oxidation Resistance and Compression Behavior of Vanadium Alloys

open access: yesAdvanced Engineering Materials, EarlyView.
An increase in oxidation resistance at 600 °C is achieved for alloys containing more than 2.5 wt.% MgO. It has been established that, along with V2O5, MgO6V2, and Mg2O7V2 are formed, which are presumed to enhance oxidative stability. Furthermore, the possible transformation of Mg‐vanadates through reaction with CO2, which presumably occurs in this ...
Ievgen Solodkyi   +5 more
wiley   +1 more source

AI-Based Estimate of the Regional Effect of Orthokeratology Lenses on Tear Film Quality

open access: yesBioengineering
Purpose: To investigate regional changes in tear film quality associated with orthokeratology (Ortho-K) lens wear using high-resolution spatial mapping and to evaluate the potential of artificial intelligence (AI) models in anticipating these changes ...
Lo-Yu Wu   +7 more
doaj   +1 more source

A Prospective Analytical Study to Study the Characteristics of Tear Film in Patients of Rheumatoid Arthritis before and after Immunosuppressant Therapy [PDF]

open access: yesJournal of Medical Academics
Background: Rheumatoid arthritis (RA), a systemic autoimmune disorder, frequently presents with ocular manifestations, notably dry eye disease (DED), due to immune-mediated damage to the lacrimal and meibomian glands.
Bhavana B Survase   +3 more
doaj   +1 more source

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

open access: yesAdvanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan   +4 more
wiley   +1 more source

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