Results 71 to 80 of about 1,480,024 (179)

Uniform Microscale Thermoresponsive Liposomes for Controlled Release Above Body Temperature

Small, Volume 22, Issue 48, 26 August 2026.
Uniform thermoresponsive liposomes are generated using a scalable double‐emulsion microfluidic approach coupled with accelerated solvent extraction. The resulting liposomes remain stable at physiological temperature but undergo abrupt rupture and cargo release at 41°C–45°C, providing a versatile platform for thermally triggered controlled release in ...
S. Morteza Mousavi, Yang Zhang, Elvis Pandzic, David W. Inglis, Megan S. Lord, Robert A. Taylor, Ming Li   +6 more
wiley   +1 more source

Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease [PDF]

, 2020
The prevalence of dry eye disease is high worldwide and poses a great burden on patients daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is believed to be the disease marker and
Yazdani, Mazyar,, Vitelli, Valeria,, Tashbayev, Bezhod,, Utheim, Tor Paaske, Ræder, Sten, Dartt, Darlene Ann, Dartt, Darlene A., Lagali, Neil, Lagali, Neil Satish, Utheim, Oygunn Aass, Dartt, Darlene A.,, Raeder, Sten, Utheim, Tor Paaske,, Jensen, Janicke Cecilie Liaaen, Tashbayev, Bezhod, Vitelli, Valeria, Chen, Xiangjun,, Jensen, Janicke Liaaen, Chen, Xiangjun, Tashbayev, Behzod, Utheim, Oygunn Aass,, Jensen, Janicke Liaaen,, Utheim, Øygunn Aass, Yazdani, Mazyar, Lagali, Neil,, Raeder, Sten,   +25 more
core   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Topical Osmoprotectant for the Management of Postrefractive Surgery-Induced Dry Eye Symptoms: A Randomised Controlled Double-Blind Trial

Journal of Ophthalmology, 2018
Background. Dry eye disease (DED) is one of the most common complications following refractive surgery. Purpose. Evaluate the efficacy of an osmoprotective eye drop (Optive®) for the management of induced DED in refractive surgery patients.
R. M. Hazarbassanov, N. G. T. Queiroz-Hazarbassanov, J. N. Barros, J. A. P. Gomes   +3 more
doaj   +1 more source

Tear osmolarity and dry eye symptoms in diabetics

, 2014
Nicole Fuerst,1 Nicole Langelier,1 Mina Massaro-Giordano,1 Maxwell Pistilli,1 Kalliopi Stasi,1 Carrie Burns,2 Serena Cardillo,2 Vatinee Y Bunya1 1Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA;
Bunya VY, Cardillo S, Stasi K, Pistilli M, Fuerst N, Massaro-Giordano M, Burns C, Langelier N   +7 more
core  

TFOS DEWS II Tear Film Report [PDF]

, 2017
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears and how these change in DED.
Holopainen, JM, Jones, L, Ucakhan, Omur O., Tom J. Millar, Stahl, Ulrike, Schmidt, TA, Papas, Eric B., Georgiev, GA, Juha M. Holopainen, Willcox, MDP ; https://orcid.org/, Omür Ö. Uçakhan, Laurie, GW, Gordon W. Laurie, Georgi A. Georgiev, Schmidt, Tannin A., Lakshman N. Subbaraman, Suarez, Tatiana M., Papas, EB ; https://orcid.org/, Stahl, U, Subbaraman, Lakshman N., Argueso, Pablo, Willcox, Mark D. P., Eric B. Papas, Suarez, T, Rolland, Jannick P., Jones, Lyndon W., Subbaraman, LN, Georgiev, Georgi A., Jones, Lyndon, Tannin A. Schmidt, Lyndon Jones, Rolland, JP, Uçakhan, O, Mark D.P. Willcox, Pablo Argüeso, Jannick P. Rolland, Papas, Eric, Argüeso, P, Laurie, Gordon W., Tatiana Suarez, Holopainen, Juha M., Suarez, Tatiana, Millar, Tom J., Millar, TJ, Millar, Thomas (R8217), Ulrike Stahl   +45 more
core   +1 more source

Dry eye disease and its treatment in women over 45 years [PDF]

Клиническая офтальмология, 2021
E.A. Drozdova1, V.E. Balan2 1South Ural State Medical University, Chelyabinsk, Russian Federation 2Moscow Regional Research Institute of Obstetrics & Gynecology, Moscow,   Russian Federation Epidemiological studies demonstrate an ...
E.A. Drozdova, V.E. Balan
doaj  

Randomized comparison of lipid‐containing and non‐lipid‐containing artificial tears on tear film dynamics over a 3‐month period

Optometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose To study the effects of a lipid‐containing artificial tear (AT) and a non‐lipid‐containing AT on tear film dynamics over a 3‐month period. Methods Subjects with low lipid layer thickness were randomized to lipid‐containing or non‐lipid‐containing ATs for 3 months.
Jennifer E. Ding, Anisha Pradhan, Dorothy K. Ma, Andrea J. FazioLiu, Sarah M. Chang, Andrew D. Graham, Devin J. Leung, Ryan S. Wu, Yixiu Zhou, Tatyana Svitova, Thao N. Yeh, Meng C. Lin   +11 more
wiley   +1 more source

Ocular surface status in patients with hemifacial spasm under long-lasting treatment with botulinum A toxin: A comparative fellow eye study

Indian Journal of Ophthalmology, 2019
Purpose: The purpose of this study was to assess the effect of long-lasting botulinum A toxin injections on ocular surface parameters and to further investigate the relationship between these parameters and the duration of the treatment. Methods: In this
Marco Pellegrini, Costantino Schiavi, Leonardo Taroni, Stefano Sebastiani, Federico Bernabei, Matilde Roda, Fabiana Moscardelli, Giuseppe Giannaccare   +7 more
doaj   +1 more source

Ocular dryness assessment in Saudi employees working indoors and outdoors

Clinical Optometry, 2018
Raied Fagehi,1 Hani Ghazal,2 Saad Alrabiah,2 Ali Abusharha,1 Saud Alanazi,1 Ali Alsaqr,1 Ali Masmali3 1Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia; 2Ophthalmology Department, King Fahad Medical
Fagehi R, Ghazal H, Alrabiah S, Abusharha A, Alanazi S, Alsaqr A, Masmali A   +6 more
doaj