Results 91 to 100 of about 90,981 (315)
Screenworks, 2020 Mirrors and Tears, is a short film by Pavel Prokopic which explores the potential of film to give rise to a feeling of meaning (affective significance) by combining chance, aspects of audio-visual style and nuances of performance – offsetting, in the process, a coherent sense of space, story and fictional characters.
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Nonlinear evolution of weakly coupled double tearing modes with equilibrium sheared toroidal flow
Nuclear FusionThe nonlinear evolution of weakly coupled double tearing modes (DTMs) with and without sheared toroidal flow is systematically investigated with the three-dimensional, toroidal-geometry, and nonlinear magneto-hydro-dynamics code CLT. Due to the explosive
Y. Y. Ying +5 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Hot tearing susceptibility of aluminum alloys using CRCM-Horizontal mold
Results in Physics, 2017 Hot tearing is one of the common defects in casting products. Hot tearing susceptibility (HTS) is evaluated using three casting temperatures: 710, 760 and 810 °C.
H. Akhyar +3 more
doaj
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Emerging Infectious Diseases, 2009 What do I do My little one, Lying oh so low? Is all that I do For me or for you, Hoping for a cure? Do I take your hand, Do I let you lie, Do I leave you alone in the snow? To do no harm, To close my bag, To treat you with nothing but tears.
openaire +3 more sources
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source