Results 131 to 140 of about 442,895 (373)

DLTM: a deep learning method for tearing mode simulation and prediction

Nuclear Fusion
Tearing modes are harmful magnetohydrodynamic instabilities in tokamaks that reduce plasma confinement by altering the magnetic field and forming magnetic islands.
Zhipeng Chang, Baofeng Gao, Ruijie Yin, Xiaofei Zhao   +3 more
doaj   +1 more source

Investigating hot tearing in 6xxx-series aluminium alloys: A combined thermodynamic and experimental approach

Journal of Alloys and Metallurgical Systems
The hot tearing of 6xxx-series aluminium alloys has been investigated over four levels of silicon (0.6, 0.8, 1.0, 1.2 wt%), magnesium (0.4, 0.6, 0.8, 1.0 wt%), iron (0.2, 0.4, 0.6, 0.8 wt%) and manganese (0.0, 0.2, 0.4, 0.6 wt%).
Emidio Giansante, Alberto Fabrizi, Mohammad Pourgharibshahi, Giulio Timelli   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Non-linear tearing of 3D null point current sheets [PDF]

, 2014
P. F. Wyper, D. I. Pontin
openalex   +1 more source

Ocular Manifestations and Tear or Conjunctival Swab PCR Positivity For SARS-CoV-2 In Patients With COVID-19: A Systematic Review and Meta-Analysis

, 2023
Anusuya Bhattacharyya
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An interferometric method for the dynamic evaluation of the tear film [PDF]

, 2006
Dorota H. Szczȩsna, Henryk T. Kasprzak, Jarosław W. Jaronski, Allan Rydz, Ulf Stenevi   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Influence of plasma density gradient on the tearing mode with the poloidal shear flow

AIP Advances
The influence of the plasma density gradient on the m/n = 2/1 and m/n = 4/1 (m is the poloidal mode number and n is the toroidal mode number) tearing mode instability with poloidal flow and flow shear is investigated.
Yue Ming, Wenjia Wang
doaj   +1 more source