Results 131 to 140 of about 255,988 (347)

Macroscopic trends of neoclassical tearing stability in high-field H-mode tokamak pilot plants

open access: yesNuclear Fusion
The neoclassical tearing mode (NTM) stability metric—minimum marginally stable island width $w_m^*$ —was compared across 14651 inductive high-field tokamak pilot plant equilibria.
S. Benjamin   +8 more
doaj   +1 more source

Effects of Tearing on the Perception of Facial Expressions of Emotion

open access: yesEvolutionary Psychology, 2015
What is the function of emotional tearing? Previous work has found a tear effect, which resolves ambiguity in neutral expressions and increases perceptions of sadness in sad expressions. Tearing, however, is associated with a variety of emotional states,
Lawrence Ian Reed   +2 more
doaj   +1 more source

Calculations in the theory of tearing instability [PDF]

open access: yes
Recent studies have suggested that the tearing instability may play a significant role in magnetic turbulence. In this work we review the theory of the magnetohydrodynamic tearing instability in the general case of an arbitrary tearing parameter, which ...
Stanislav Boldyrev, Nuno F. Loureiro
core   +3 more sources

3D reconnection due to oblique modes: a simulation of Harris current sheets [PDF]

open access: yesNonlinear Processes in Geophysics, 2000
Simulations in three dimensions of a Harris current sheet with mass ratio, mi/me = 180, and current sheet thickness, pi/L = 0.5, suggest the existence of a linearly unstable oblique mode, which is independent from either the drift-kink or the tearing ...
G. Lapenta, G. Lapenta, J. U. Brackbill
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Response of thin circular plates to central blast loading [PDF]

open access: yes, 1996
Includes bibliographical references.The large ductile deformation response and rupture of thin circular metal plates subjected to central blast loading is investigated using the ABAQUS general purpose finite element code.
Bimha, Richard Ernest
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Tearing Down [PDF]

open access: yes, 1970
Photograph used for a story in the Daily Oklahoman newspaper. Caption: "TEARING DOWN the old bridge over the North Canadian River near Watonga, workmen make path for progress and new bride construction in background.
Heaton, Dave
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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