Results 151 to 160 of about 442,895 (373)

Epigenetic regulation of metalloproteinases and their inhibitors in rotator cuff tears

, 2017
Mariana Ferreira Leal, Leonardo Caires Santos, Adrielle Martins de Oliveira, Paulo Santoro Belangero, Eduardo Antônio de Figueiredo, Carina Cohen, Felipe de Seixas Alves, Wânia Hiromi Yanaguizawa, Carlos Vicente Andreoli, Alberto de Castro Pochini, Benno Ejnisman, Marı́lia de Arruda Cardoso Smith, Maria Teresa de Seixas Alves, Moisés Cohen   +13 more
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Reusing Textiles: on Material and Cultural Wear and Tear

, 2015
Anneli Palmsköld
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Clinical Evidence for Suture Anchor Repair of Rotator Cuff Tears Does Add Up: Some Just Do Not Want to See It [PDF]

, 2010
Nicola Maffulli, Francesco Franceschi, Umile Giuseppe Longo, Laura Ruzzini, Vincenzo Denaro   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Magnetic Island Structures Associated with Kinetic Alfvén Solitary Wave in Two-fluid Plasma

The Astrophysical Journal
We investigate the formation of magnetic islands and the onset of tearing instability within kinetic Alfvén solitary waves in a two-fluid space plasma. These localized structures, featuring internal magnetic shear, naturally support magnetic reconnection
Cheong R. Choi, M.-H. Woo, Peter H. Yoon, Kwangsun Ryu, H. K. Cho, Jungjoon Seough, D.-Y. Lee   +6 more
doaj   +1 more source

The impact of pseudoexfoliation and arteficial tear application on tear film stability in a pseudophakic eye

, 2017
Dušan Todorović, Tatjana Šarenac-Vulović, Svetlana Jovanović, Mirjana Janićijević-Petrović, Nenad Petrović, Marko Kontic, Milos Todorovic, Katarina Janićijević, Sunčica Srećković   +8 more
openalex   +2 more sources

Paper #208 The supraspinatus footprint: a rationale guide for the management of articular sided partial thickness supraspinatus tears [PDF]

, 2003
Wesley M. Nottage, Charles Ruotolo, Marc R. Safran   +2 more
openalex   +1 more source