Results 81 to 90 of about 90,090 (290)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Percentage Level of Tannin fur Rabbit for Leather Concerning Stitch Tearing Strength, Tearing Strength and Flexibility

open access: yesJurnal Ilmu dan Teknologi Hasil Ternak, 2012
The purpose of this study was to find out the appropriate of tannin level for rabbit fur leather concerning stitch tearing strength, tearing strength, and flexibility.
Mustakim Mustakim   +2 more
doaj  

Tearing: Breakthrough in Human Emotional Signaling

open access: yesEvolutionary Psychology, 2009
Tearing is not a benign secretory correlate of sadness or other emotional state, but a potent visual cue that adds meaning to human facial expression, the tear effect .
Robert R. Provine   +2 more
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Structural parameters affecting tear strength of the fabrics tents

open access: yesAlexandria Engineering Journal, 2018
The tearing strength is more vital in heavy duty fabrics. So it is important to know the effects of the fabric structural parameters on the tearing resistance of these types of fabrics.
Eman Eltahan
doaj  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Effect of Y content on hot tearing susceptibility of MgZn9YxZr0.5 alloys

open access: yesCailiao gongcheng, 2019
Based on the Clyne-Davies model,the hot tearing susceptibility(CSC)of MgZn9YxZr0.5(x=1,2,4,6,mass fraction/%) was predicted.The microstructure and morphology of hot tearing regions of the alloys were observed by X-ray diffraction (XRD) and scanning ...
JIA Dong-rui   +5 more
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

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