Results 191 to 200 of about 1,047,530 (303)

Architected Inverse Nacre Hydrogels With High Strength and Crack-Insensitive Toughness. [PDF]

Adv Sci (Weinh)
Wu H, Su Q, Guan C, Pan B, Hu W, Yan J, Feng Y, Tang L, Huang X, Gao J, Gu W.   +10 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

From Intrinsic Resin Properties to Interlaminar Fracture Toughness of CFRP: Crack-Tip Deformation, Transfer Mechanisms, and Loading-Mode Dependence. [PDF]

Polymers (Basel)
Li X, Ou Y, Li J, Weng Y, Zhang Y, Fu A, Liu X, Huang Q, Mao D.   +8 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Planned cesarean section or attempted vaginal delivery: Which is more environmentally friendly? An observational life cycle assessment study in France. [PDF]

Acta Obstet Gynecol Scand
Jaafar S, Gillani S, Cordier S, Garabedian C.   +3 more
europepmc   +1 more source

Surface Tearing Modes in Tokamaks

Surface Tearing Modes in Tokamaks
トカマクにおける表面ティアリングモードについて数値的、解析的に調べた。成長率およびモードの構造を固有値問題として求めた。モード数m=2、n=1の抵抗性MHDモードの成長率について詳しく調べ、プラズマ表面の安全係数、電流分布、導体壁の位置、抵抗に対する依存性を明らかにした。導体壁がプラズマ表面に近くなったときでも、表面ティアリングモードによってプラズマ表面は動かされる。これらのモードに関する安定性図表を示した。
openaire   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Effect of Selectively Etched Al-Rich and Si-Rich Microstructures on the Adhesion of Polyimide Coatings to SLM AlSi10Mg. [PDF]

Materials (Basel)
Li J, Yang S, Li Y.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Effect of Grain-Boundary Discontinuous Precipitation Evolution on the Transition of Creep-Rupture Failure Modes in Ni-Fe-Based Alloy/Inconel 617 Dissimilar Welded Joints. [PDF]

Materials (Basel)
Li L, Li S, Fan M, Cheng J, Zhang W, Huo X, Liu X, Li K, Cai Z, Liu Q.   +9 more
europepmc   +1 more source