Results 91 to 100 of about 513,929 (290)
Tear protein analysis in presumed congenital alacrima
Clinical Ophthalmology, 2018 Shigeharu Yaginuma,1 Yoko Akune,2 Chika Shigeyasu,1,2 Yoji Takano,3 Masakazu Yamada1 1Department of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, Japan; 2Division for Vision Research, National Institute of Sensory Organs, National
Yaginuma S +4 more
doaj
Proteomes, 2015 We produced a tear proteome of the genome mouse, C57BL/6, that contained 139 different protein identifications: 110 from a two-dimensional (2D) gel with subsequent trypsin digestion, 19 from a one-dimensional (1D) gel with subsequent trypsin digestion ...
Robert C. Karn, Christina M. Laukaitis
doaj +1 more source
Prognostic factors for aorta remodeling after thoracic endovascular aortic repair of complicated chronic DeBakey IIIb aneurysms [PDF]
, 2014 ObjectivesThe use of thoracic endovascular aortic repair (TEVAR) for chronic DeBakey III type b (CDIIIb) aneurysms is controversial. We analyzed the potential prognostic factors affecting aorta remodeling after this procedure.MethodsA total of 20 ...
Cho, Bum-Koo +5 more
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
How Geometry Controls the Tearing of Adhesive Thin Films on Curved Surfaces [PDF]
, 2011 Flaps can be detached from a thin film glued on a solid substrate by tearing and peeling. For flat substrates, it has been shown that these flaps spontaneously narrow and collapse in pointy triangular shapes. Here we show that various shapes, triangular,
Didier Villers +4 more
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Differences in Risk Factors for Rotator Cuff Tears between Elderly Patients and Young Patients [PDF]
, 2018 It has been unclear whether the risk factors for rotator cuff tears are the same at all ages or differ between young and older populations. In this study, we examined the risk factors for rotator cuff tears using classification and regression tree ...
Hirooka, Takahiko +4 more
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FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease
eLife, 2020 Meibum lipids form a lipid layer on the outermost side of the tear film and function to prevent water evaporation and reduce surface tension. (O-Acyl)-ω-hydroxy fatty acids (OAHFAs), a subclass of these lipids, are thought to be involved in connecting ...
Masatoshi Miyamoto +3 more
doaj +1 more source
I\u27d weep with thee, if tears could keep,The memories of the past from me,I\u27d weep with thee, if tears could keep The memories of the past from me,Or happier far if I could weep,One hour of gladness back to thee;Or happier far if I could weepOne ...
Weber, Carl Maria von
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