Results 41 to 50 of about 571,926 (291)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Tear antibodies to SARS‐CoV‐2: implications for transmission

open access: yesClinical & Translational Immunology, 2021
Objectives SARS‐CoV‐2 can be transmitted by aerosols, and the ocular surface may be an important route of transmission. Little is known about protective antibody responses to SARS‐CoV‐2 in tears after infection or vaccination.
Kevin J Selva   +10 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Prospective data collection and analysis of perforations and tears of latex surgical gloves during primary endoprosthetic surgeries

open access: yesGMS Hygiene and Infection Control, 2016
Introduction: Surgical gloves are used to prevent contamination of the patient and the hospital staff with pathogens. The aim of this study was to examine the actual effectiveness of gloves by examining the damage (perforations, tears) to latex gloves ...
Zaatreh, Sarah   +6 more
doaj   +1 more source

The collection of sententiae associated with the mimographer Publilius and its portrayal of laughter, tears, and silence [PDF]

open access: yes, 2013
The purpose of this paper is two-fold: to provide an up-to-date overview of the main problems pertaining to the purpose and transmission of a collection of apophthegms (sententiae), associated with the mime-actor and mimographer Publilius, and to discuss
Panayotakis, Costas
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review

open access: yesDiseases, 2018
Congenital nasolacrimal duct obstruction (CNLDO) is a common condition causing excessive tearing or mucoid discharge from the eyes, due to blockage of the nasolacrimal duct system.
Aldo Vagge   +6 more
doaj   +1 more source

Ocular Surface Features in Patients with Parkinson Disease on and off Treatment: A Narrative Review

open access: yesLife, 2022
Parkinson disease (PD) is a progressive, neurodegenerative disease of the central nervous system. Visual disturbance is one of the most frequent nonmotor abnormalities referred to by patients suffering from PD at early stages. Furthermore, ocular surface
Matilde Buzzi   +7 more
doaj   +1 more source

Typologies of Black Male Sensitivity in R&B and Hip Hop [PDF]

open access: yes, 2014
A qualitative content analysis was conducted on the lyrics of 79 R&B and Hip Hop songs from 1956-2013 to identify the ways that these Black male artists expressed sensitivity.
Chaney, Cassandra, Mincey, Krista D.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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