Results 51 to 60 of about 580,966 (311)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Imaging-Based Prevalence of Superior Labral Anterior-Posterior Tears Significantly Increases in the Aging Shoulder. [PDF]

open access: yes, 2018
BackgroundSuperior labral anterior-posterior (SLAP) tears can be associated with pain and shoulder dysfunction. Relatively little is known about the age-related prevalence of SLAP tears.PurposeTo investigate the age-related prevalence of imaging ...
Bendich, Ilya   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Transcendental Idealism Without Tears [PDF]

open access: yes, 2017
This essay is an attempt to explain Kantian transcendental idealism to contemporary metaphysicians and make clear its relevance to contemporary debates in what is now called ‘meta-metaphysics.’ It is not primarily an exegetical essay,
Stang, Nicholas
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Prospective data collection and analysis of perforations and tears of latex surgical gloves during primary endoprosthetic surgeries

open access: yesGMS Hygiene and Infection Control, 2016
Introduction: Surgical gloves are used to prevent contamination of the patient and the hospital staff with pathogens. The aim of this study was to examine the actual effectiveness of gloves by examining the damage (perforations, tears) to latex gloves ...
Zaatreh, Sarah   +6 more
doaj   +1 more source

Tear antibodies to SARS‐CoV‐2: implications for transmission

open access: yesClinical & Translational Immunology, 2021
Objectives SARS‐CoV‐2 can be transmitted by aerosols, and the ocular surface may be an important route of transmission. Little is known about protective antibody responses to SARS‐CoV‐2 in tears after infection or vaccination.
Kevin J Selva   +10 more
doaj   +1 more source

The collection of sententiae associated with the mimographer Publilius and its portrayal of laughter, tears, and silence [PDF]

open access: yes, 2013
The purpose of this paper is two-fold: to provide an up-to-date overview of the main problems pertaining to the purpose and transmission of a collection of apophthegms (sententiae), associated with the mime-actor and mimographer Publilius, and to discuss
Panayotakis, Costas
core  

Equivalent Mid-Term Results of Open vs Endoscopic Gluteal Tendon Tear Repair Using Suture Anchors in Forty-Five Patients. [PDF]

open access: yes, 2020
BackgroundLittle is known about the relative efficacy of open (OGR) vs endoscopic (EGR) gluteal tendon repair of gluteal tendon tears in minimizing pain and restoring function.
Bini, Stefano A   +5 more
core  

Tears for the Fallen [PDF]

open access: yesThe Permanente Journal, 2016
“Trauma 99 activation, ETA 5 min!” As an emergency medicine resident, this type of overhead page is what gets my adrenaline pumping. Finally, I thought, I’ve been waiting for some action all night. I looked over at the call sheet: 30-year-old male, single gunshot wound to the torso, CPR in progress.
openaire   +2 more sources

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