Results 41 to 50 of about 146,962 (315)

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source

Post-translation modification of proteins in tears [PDF]

, 2010
This is the first 2-DE study using sequential dyes to analyse phospho-, glyco- and total tear protein profiles (Pro-Q Diamond for phosphoprotein, Pro-Q Emerald for glycoprotein and Sypro Ruby for total protein).
Walsh, Bradley J., Li, Yong, Cozzi, Paul J., Ling Zhong, Wasinger, Valerie, Graham, Peter, Pamela J. Russell, Walsh, Bradley, You, Jingjing, Paul J. Cozzi, Yong Li, Zhenjun Zhao, Willcox, Mark, Anna Fitzgerald, Zhong, Ling, Russell, Pamela J., Valerie Wasinger, Fitzgerald, Anna, Bradley J. Walsh, Cozzi, Paul, Zhao, Zhenjun, Jingjing You, Russell, Pamela, Peter Graham, Mark Willcox   +24 more
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Prospective data collection and analysis of perforations and tears of latex surgical gloves during primary endoprosthetic surgeries

GMS Hygiene and Infection Control, 2016
Introduction: Surgical gloves are used to prevent contamination of the patient and the hospital staff with pathogens. The aim of this study was to examine the actual effectiveness of gloves by examining the damage (perforations, tears) to latex gloves ...
Zaatreh, Sarah, Enz, Andreas, Klinder, Annett, König, Tony, Mittelmeier, Lena, Kundt, Günther, Mittelmeier, Wolfram   +6 more
doaj   +1 more source

Tear antibodies to SARS‐CoV‐2: implications for transmission

Clinical & Translational Immunology, 2021
Objectives SARS‐CoV‐2 can be transmitted by aerosols, and the ocular surface may be an important route of transmission. Little is known about protective antibody responses to SARS‐CoV‐2 in tears after infection or vaccination.
Kevin J Selva, Samantha K Davis, Ebene R Haycroft, Wen Shi Lee, Ester Lopez, Arnold Reynaldi, Miles P Davenport, Helen E Kent, Jennifer A Juno, Amy W Chung, Stephen J Kent   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Artificial tears potpourri: a literature review [PDF]

, 2014
Majid Moshirfar,1 Kasey Pierson,2,* Kamalani Hanamaikai,3,* Luis Santiago-Caban,1 Valliammai Muthappan,1 Samuel F Passi11Department of Ophthalmology, John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 2University of Arizona College of ...
Hanamaikai K, Santiago-Caban L, Muthappan V, Pierson K, Passi SF, Moshirfar M   +5 more
core  

Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review

Diseases, 2018
Congenital nasolacrimal duct obstruction (CNLDO) is a common condition causing excessive tearing or mucoid discharge from the eyes, due to blockage of the nasolacrimal duct system.
Aldo Vagge, Lorenzo Ferro Desideri, Paolo Nucci, Massimiliano Serafino, Giuseppe Giannaccare, Andrea Lembo, Carlo Enrico Traverso   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases

Frontiers in Medicine
Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing ...
Fushen Zhang, Weiye Xu, Zejun Deng, Jufang Huang   +3 more
doaj   +1 more source