Results 51 to 60 of about 19,007 (252)

»Techne liebt Tyche und Tyche Techne«

open access: yes, 2008
Die folgenden Überlegungen wollen die Frage künstlerischer Kreativität im Horizont des aristotelischen Denkens diskutieren. Künstlerische Kreativität ist in der Neuzeit in besonderer Weise zum Ausweis eines autonomen Subjektes geworden. Die Geschichte dieses Konzeptes hat dabei den Gegensatz von kreativer Autonomie und reproduktiv-imitativem ...
openaire   +2 more sources

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

The Accidental Meeting

open access: yes, 2022
This is a ballad in the form of poetry ...
Wijesuriya, Anika
core  

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

open access: yesInterdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen   +6 more
wiley   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati   +6 more
wiley   +1 more source

Logos, techne e virtualità

open access: yes, 2017
logos, techne, concetto di virtuale, ontologia del ...
Diodato, Roberto
core  

The Practical-Technical Reason in the Aristotelian Concept of the Faculties of the Soul

open access: yesPeitho, 2017
When analyzing the structure of the soul, Aristotle distinguished three faculties: the theoretical, the practical and the technical one. The latter two are the focus of this paper.
Aleksandra Mathiesen
doaj   +1 more source

Frequency of ZFHX3‐Mediated Spinocerebellar Ataxia 4 in a US Undiagnosed Ataxia Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia 4 (SCA4) is a late‐onset dominant ataxia with neuropathy caused by exonic GGC repeat expansion in the ZFHX3 gene thought to originate from a Swedish founder event. The GC‐rich expansion is highly thermodynamically stable, posing challenges for standard clinical genetic testing methods.
Annie Chen   +320 more
wiley   +1 more source

Techné/Technology [PDF]

open access: yes, 2014
This fourth title in the series The Key Debates sets out where the term techne comes from, how it unleashed a revolution in thought and how the concept in the midst of the current digital revolution, once again, is influencing the study of film.

core   +2 more sources

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