Results 91 to 100 of about 85,906 (293)

Congenital Hypothyroidism: Long‐Term Growth and Intellectual Outcomes With a Lower Initial Levothyroxine Dose

open access: yesClinical Endocrinology, Volume 103, Issue 6, Page 895-905, December 2025.
ABSTRACT Objectives This study aims to review the long‐term outcome of congenital hypothyroidism (CH) and whether patient‐ or treatment‐related factors impact the outcomes, especially focusing on the initial Levothyroxine dose. Methods This is a retrospective, cross‐sectional study of the children diagnosed with CH who received Levothyroxine at Ajou ...
Jun‐Hong Park   +4 more
wiley   +1 more source

Surgical Treatment for Osteomalacia Induced by Causative Tumor in the Knee Joint Region: A Single‐Center Retrospective Clinical Study Over 10 Years

open access: yesOrthopaedic Surgery, Volume 17, Issue 12, Page 3440-3455, December 2025.
The causative tumor for TIO in the knee joint region is hidden and has diverse locations, resulting in great challenges to endocrinologist and orthopedists. Due to the unique anatomical location and complex structure of the knee joint, orthopedic surgeons can adopt different surgical approaches to completely remove the causative tumor.
Shuzhong Liu   +7 more
wiley   +1 more source

The use of (99m}Tc-Al[2]O[3] for detection of sentinel lymph nodes in breast cancer [PDF]

open access: yes, 2000
Purpose: to study the feasibility of using the new radiopharmaceutical based on the technetium-99m-labeled gamma-alumina for identification of sentinel lymph nodes (SLNs) in breast cancer patients.
Sinilkin, Ivan Gennadjevich   +7 more
core   +1 more source

The contemporary management of prostate cancer

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 552-586, November/December 2025.
Abstract Prostate cancer is the most common cancer in two thirds of the world, with an expected doubling in both incidence and mortality in the next two decades. No strong environmental associations exist for the development of prostate cancer; therefore, lifestyle measures are unlikely to mitigate this increasing burden.
Deep Chakrabarti   +11 more
wiley   +1 more source

Computational Study of Drug Delivery Systems with Radionuclide and Fluorescence Imaging Modalities. III. Doxorubicin Delivery Systems Based on Albumin and Lysozyme

open access: yesEast European Journal of Physics
This study investigates the development of advanced protein-based drug delivery systems for doxorubicin (DOX) by integrating lysozyme into albumin-based carriers, incorporating both radionuclide (technetium-99m complexes) and fluorescence (near-infrared ...
V. Trusova   +9 more
doaj   +1 more source

Reduced uptake of the proliferation-seeking radiotracer technetium-99m-labelled pentavalent dimercaptosuccinic acid in a 47-year-old woman with severe breast epithelial hyperplasia taking ibuprofen: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Recent studies have reported a risk reduction in the progression of benign breast disease to breast carcinoma through COX-2 pathways. Case presentation We present a case of severe epithelial hyperplasia in a 47-year-old woman with increased ...
Marinopoulos Spyridon G   +10 more
doaj   +1 more source

Evaluation of two 99mTc-DTPA radioaerosols with different characteristics in lung ventilation studies [PDF]

open access: yes, 2003
Two radioaerosol preparations, TechneScan®-DTPA (99mTc-DTPA, 40 mCi/3 ml; IPEN-CNEN, São Paulo, SP, Brazil) and TechneScan®-DTPA/AEROSOL (99mTc-DTPA/A, 15 mCi/1.5 ml with 0.5 ml ethanol; Mallinckrodt Medical, St.
Castiglioni, M.l.v.   +4 more
core   +4 more sources

A patient with newly diagnosed breast cancer found to have mosaic TP53 likely pathogenic variant

open access: yes
CA: A Cancer Journal for Clinicians, EarlyView.
Hetal D. Mistry   +8 more
wiley   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 11, Page 2181-2192, November 2025.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang   +7 more
wiley   +1 more source

99mTc Labelling Strategies for the Development of Potential Nitroimidazolic Hypoxia Imaging Agents

open access: yesInorganics, 2019
Technetium-99m has a rich coordination chemistry that offers many possibilities in terms of oxidation states and donor atom sets. Modifications in the structure of the technetium complexes could be very useful for fine tuning the physicochemical and ...
Javier Giglio, Ana Rey
doaj   +1 more source

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