Results 51 to 60 of about 22,718 (165)

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

Drug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal, Akanksha Jain, Ashwini Babu, Chandan Kumar, Madhava B. Mallia   +4 more
wiley   +1 more source

Incidental Finding of Triple Ectopic Thyroid: Case Report and Review of the Literature [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology
Ectopic thyroid tissue is a rare congenital anomaly, with the presence of three simultaneous ectopic foci being exceedingly rare. We describe a case of a totally asymptomatic 26-year-old male discovered to have triple ectopic thyroid following incidental
Fatima Zeineddine, Gerard El-Hajj, Marie-Ange Hajj, Rita Chahinian   +3 more
doaj   +1 more source

18‐FDG PET in the Evaluation of Therapeutic Response of Necrotizing Otitis Externa

The Laryngoscope, Volume 136, Issue 2, Page 961-971, February 2026.
PET performed well in assessing the therapeutic response of NEO, with excellent sensitivity but low specificity of visual analysis. A complementary quantitative analysis was useful to distinguish between satisfactory and insufficient partial responses. ABSTRACT Objective The duration of antibiotic treatment for necrotizing otitis externa (NEO) and the ...
Lucie Lécolier, Philippine Toulemonde, Damien Huglo, Clio Baillet, Pauline Thill, Gauthier Delaby   +5 more
wiley   +1 more source

Technetium-99m ceftizoxime kit preparation

Brazilian Archives of Biology and Technology, 2005
The aim of this work was to prepare a kit of 99mTc-ceftizoxime (99mTc-CFT), with stability and biological activity preserved, able to identify a septic focus (E. coli) in the experimental infection model in rats.
Simone Odília Fernandes Diniz, Cristiano Ferrari Siqueira, David Lee Nelson, Josep Martin-Comin, Valbert Nascimento Cardoso   +4 more
doaj   +1 more source

Incidental breast lesion detected by technetium-99m sestamibi scintigraphy in a patient with primary hyperparathyroidism

World Journal of Nuclear Medicine, 2020
Nuclear scintigraphy is functional imaging and can be combined with anatomical imaging to improve diagnostic yield. Detection of parathyroid lesion by technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) can facilitate an appropriate operative approach
Sakditad Saowapa, Wichana Chamroonrat, Ronnarat Suvikapakornkul, Chutintorn Sriphrapradang   +3 more
doaj   +1 more source

Comprehensive Analysis and Quality Assessment of Freeze Dried Methylene Diphosphonate Labelled with 99m-Technetium: An Extensive Comparison of  Biodistribution Study with Commercial Standards [PDF]

, 2023
Kifyat Tasnim, Rabeya Akhter, Mustafizur Rahman, Md Anwar Hossain, Momtaz Fatima Waheed, Fatema Tuj Jahura, Sultanur Reza, Debasish Chowdhury, Ruhul Amin, Tariqul Islam, Azizul Haque, Md. Jashim Uddin   +11 more
openalex   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 229-240, January 2026.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai, Kosuke Matsui, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Hisashi Kosaka, Van Khanh Nguyen, Yasuhiro Ueno, Shuji Kariya, Masaki Kaibori   +9 more
wiley   +1 more source

RADIOPHARMACEUTICALS BASED ON THE GLUCOSE DERIVATIVES FOR TUMOR DIAGNOSIS

Сибирский онкологический журнал, 2018
The purpose of the study was to review available literature on the efficacy of radiopharmaceuticals based on glucose derivatives labeled with radioactive isotopes for detection of various cancers. Material and methods.
R. V. Zeltchan, A. A. Medvedeva, I. G. Sinilkin, O. V. Bragina, V. J. Chernov   +4 more
doaj   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source